Literature DB >> 12224932

A photochemical route for efficient cyclopeptide formation with a minimum of protection and activation chemistry.

Axel G Griesbeck1, Thomas Heinrich, Michael Oelgemöller, Johann Lex, Arne Molis.   

Abstract

An elaborated protocol is described which allows the efficient transformation of di-, tri-, and tetrapeptides into cyclopeptides with a minimum of protection and activation chemistry using the photoinduced electron transfer initiated decarboxylation of N-phthaloyl peptides resulting in C-C coupling between the initially formed carbon radicals.

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Year:  2002        PMID: 12224932     DOI: 10.1021/ja025804o

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  2 in total

Review 1.  Photochemical Methods for Peptide Macrocyclisation.

Authors:  Laetitia Raynal; Nicholas C Rose; James R Donald; Christopher D Spicer
Journal:  Chemistry       Date:  2020-10-27       Impact factor: 5.236

2.  Decarboxylative allylation of amino alkanoic acids and esters via dual catalysis.

Authors:  Simon B Lang; Kathryn M O'Nele; Jon A Tunge
Journal:  J Am Chem Soc       Date:  2014-09-22       Impact factor: 15.419

  2 in total

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