Martha Sajatovic1. 1. Department of Psychiatry, Case Western Reserve University School of Medicine, Ohio 44106-5000, USA. martha.sajatovic@uhhs.com
Abstract
BACKGROUND: It has been reported that 10% of all patients with bipolar disorder develop their illness after the age of 50, with bipolar disorder accounting for 5-19% of mood disorder presentations in the elderly. There has been a growing awareness regarding the manifestation of bipolar disorder among older adults due to both changes in national demographics, and developing sophistication in the treatment of bipolar illness. A persistent problem in our understanding of management of late life bipolar disorder is the paucity of research and rigorous published studies on the psychopharmacology of this condition. OBJECTIVE: This paper reviews medication treatments, non-medication biological therapies, and psychosocial interventions for bipolar disorder in late life with a particular emphasis on age related modifiers of treatment. METHODS: Findings are based upon review of the current literature. RESULTS: There are multiple, significant gaps in our knowledge of bipolar disorder in late life which have important implications in the optimum treatment of elderly individuals with bipolar illness. CONCLUSION: There are a number of areas of needed future research in late life bipolar disorder. Copyright 2002 John Wiley & Sons, Ltd.
BACKGROUND: It has been reported that 10% of all patients with bipolar disorder develop their illness after the age of 50, with bipolar disorder accounting for 5-19% of mood disorder presentations in the elderly. There has been a growing awareness regarding the manifestation of bipolar disorder among older adults due to both changes in national demographics, and developing sophistication in the treatment of bipolar illness. A persistent problem in our understanding of management of late life bipolar disorder is the paucity of research and rigorous published studies on the psychopharmacology of this condition. OBJECTIVE: This paper reviews medication treatments, non-medication biological therapies, and psychosocial interventions for bipolar disorder in late life with a particular emphasis on age related modifiers of treatment. METHODS: Findings are based upon review of the current literature. RESULTS: There are multiple, significant gaps in our knowledge of bipolar disorder in late life which have important implications in the optimum treatment of elderly individuals with bipolar illness. CONCLUSION: There are a number of areas of needed future research in late life bipolar disorder. Copyright 2002 John Wiley & Sons, Ltd.
Authors: Robert C Young; Herbert C Schulberg; Ariel G Gildengers; Martha Sajatovic; Benoit H Mulsant; Laszlo Gyulai; John Beyer; Lauren Marangell; Mark Kunik; Thomas Ten Have; Martha L Bruce; Ruben Gur; Patricia Marino; Jovier D Evans; Charles F Reynolds; George S Alexopoulos Journal: Bipolar Disord Date: 2010-02 Impact factor: 6.744
Authors: Martha Sajatovic; Sergio A Strejilevich; Ariel G Gildengers; Annemiek Dols; Rayan K Al Jurdi; Brent P Forester; Lars Vedel Kessing; John Beyer; Facundo Manes; Soham Rej; Adriane R Rosa; Sigfried Ntm Schouws; Shang-Ying Tsai; Robert C Young; Kenneth I Shulman Journal: Bipolar Disord Date: 2015-09-19 Impact factor: 6.744
Authors: Brent P Forester; Chris C Streeter; Yosef A Berlow; Hua Tian; Megan Wardrop; Chelsea T Finn; David Harper; Perry F Renshaw; Constance M Moore Journal: Am J Geriatr Psychiatry Date: 2009-01 Impact factor: 4.105
Authors: Brent P Forester; Chelsea T Finn; Yosef A Berlow; Megan Wardrop; Perry F Renshaw; Constance M Moore Journal: Bipolar Disord Date: 2008-09 Impact factor: 6.744
Authors: G M Goodwin; P M Haddad; I N Ferrier; J K Aronson; Trh Barnes; A Cipriani; D R Coghill; S Fazel; J R Geddes; H Grunze; E A Holmes; O Howes; S Hudson; N Hunt; I Jones; I C Macmillan; H McAllister-Williams; D R Miklowitz; R Morriss; M Munafò; C Paton; B J Saharkian; Kea Saunders; Jma Sinclair; D Taylor; E Vieta; A H Young Journal: J Psychopharmacol Date: 2016-03-15 Impact factor: 4.153