Literature DB >> 12219069

HLA in Egyptian children with biliary atresia.

Hassan H A-Kader1, Moustafa El-Ayyouti, Samia Hawas, Ahmed Abdalla, Yousif Al-Tonbary, Mohammed Bassiouny, Anna Boneberg, Shadia El-Sallab.   

Abstract

We studied the human leukocytes antigens in 18 Egyptian children with biliary atresia (BA) without extrahepatic congenital malformations. There was a significant increased frequency of both B8 and DR3 (83.3% and 94.4% in patients with BA compared with 6.5% and 14.9% in the general population, respectively). Ten patients had the B8/DR3 haplotype. Our results support the hypothesis that genetic factors may play a role in susceptibility to BA.

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Year:  2002        PMID： 12219069     DOI： 10.1067/mpd.2002.127506

Source DB:  PubMed          Journal:  J Pediatr        ISSN： 0022-3476            Impact factor:   4.406


  6 in total

1.  Genomic alterations in biliary atresia suggest region of potential disease susceptibility in 2q37.3.

Authors:  Melissa Leyva-Vega; Jennifer Gerfen; Brian D Thiel; Dorota Jurkiewicz; Elizabeth B Rand; Joanna Pawlowska; Diana Kaminska; Pierre Russo; Xiaowu Gai; Ian D Krantz; Binita M Kamath; Hakon Hakonarson; Barbara A Haber; Nancy B Spinner
Journal:  Am J Med Genet A       Date:  2010-04       Impact factor: 2.802

2.  Cellular and humoral autoimmunity directed at bile duct epithelia in murine biliary atresia.

Authors:  Cara L Mack; Rebecca M Tucker; Brandy R Lu; Ronald J Sokol; Andrew P Fontenot; Yoshiyuki Ueno; Ronald G Gill
Journal:  Hepatology       Date:  2006-11       Impact factor: 17.425

3.  There is no association between K469E ICAM-1 gene polymorphism and biliary atresia.

Authors:  Paisarn Vejchapipat; Naruemol Jirapanakorn; Nutchanart Thawornsuk; Apiradee Theamboonlers; Voranush Chongsrisawat; Soottiporn Chittmittrapap; Yong Poovorawan
Journal:  World J Gastroenterol       Date:  2005-08-21       Impact factor: 5.742

Review 4.  Biliary atresia.

Authors:  Giorgina Mieli-Vergani; Diego Vergani
Journal:  Semin Immunopathol       Date:  2009-06-17       Impact factor: 9.623

Review 5.  The pathogenesis of biliary atresia: evidence for a virus-induced autoimmune disease.

Authors:  Cara L Mack
Journal:  Semin Liver Dis       Date:  2007-08       Impact factor: 6.115

6.  Lack of HLA predominance and HLA shared epitopes in biliary Atresia.

Authors:  Cara L Mack; Kirsten M Anderson; Michael T Aubrey; Philip Rosenthal; Ronald J Sokol; Brian M Freed
Journal:  Springerplus       Date:  2013-02-08
  6 in total

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