Literature DB >> 12217627

Degeneration of neuronal cells due to oxidative stress--microglial contribution.

E Koutsilieri1, C Scheller, F Tribl, P Riederer.   

Abstract

Various neurodegenerative disorders including Parkinson's disease, Alzheimer's disease and amyotrophic lateral sclerosis have been causally linked to the generation of free radicals and oxidative stress. In this review, we discuss the implication of oxidative stress in neuronal death and point out the role of intracellular signaling pathways leading to activation of transcription factors associated with cell death and repair. In particular, the impact of microglia as contributors in promoting oxidative stress in neurodegeneration is highlighted. Finally, pivotal molecular targets for drug therapies of brain disorders are reported.

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Year:  2002        PMID： 12217627     DOI： 10.1016/s1353-8020(02)00021-4

Source DB:  PubMed          Journal:  Parkinsonism Relat Disord        ISSN： 1353-8020            Impact factor:   4.891


  17 in total

Review 1.  Role of microglia in central nervous system infections.

Authors:  R Bryan Rock; Genya Gekker; Shuxian Hu; Wen S Sheng; Maxim Cheeran; James R Lokensgard; Phillip K Peterson
Journal:  Clin Microbiol Rev       Date:  2004-10       Impact factor: 26.132

Review 2.  Reactive oxygen/nitrogen species and their functional correlations in neurodegenerative diseases.

Authors:  Mahesh Ramalingam; Sung-Jin Kim
Journal:  J Neural Transm (Vienna)       Date:  2012-01-04       Impact factor: 3.575

3.  Particulate matter neurotoxicity in culture is size-dependent.

Authors:  Patricia Gillespie; Julianne Tajuba; Morton Lippmann; Lung-Chi Chen; Bellina Veronesi
Journal:  Neurotoxicology       Date:  2011-10-25       Impact factor: 4.294

4.  Cobinamide is effective for treatment of hydrogen sulfide-induced neurological sequelae in a mouse model.

Authors:  Poojya Anantharam; Elizabeth M Whitley; Belinda Mahama; Dong-Suk Kim; Souvarish Sarkar; Cristina Santana; Adriano Chan; Anumantha G Kanthasamy; Arthi Kanthasamy; Gerry R Boss; Wilson K Rumbeiha
Journal:  Ann N Y Acad Sci       Date:  2017-11       Impact factor: 5.691

Review 5.  Neuroprotective mechanisms of astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration.

Authors:  Bethany Grimmig; Seol-Hee Kim; Kevin Nash; Paula C Bickford; R Douglas Shytle
Journal:  Geroscience       Date:  2017-02-13       Impact factor: 7.713

6.  The antioxidant effect of astaxanthin is higher in young mice than aged: a region specific study on brain.

Authors:  Md Mamun Al-Amin; Samiha Akhter; Ahmed Tasdid Hasan; Tanzir Alam; S M Nageeb Hasan; A R M Saifullah; Mohammad Shohel
Journal:  Metab Brain Dis       Date:  2015-06-27       Impact factor: 3.584

Review 7.  How can research on plants contribute to promoting human health?

Authors:  Cathie Martin; Eugenio Butelli; Katia Petroni; Chiara Tonelli
Journal:  Plant Cell       Date:  2011-05-17       Impact factor: 11.277

8.  Microglia mediate diesel exhaust particle-induced cerebellar neuronal toxicity through neuroinflammatory mechanisms.

Authors:  Pamela J Roqué; Khoi Dao; Lucio G Costa
Journal:  Neurotoxicology       Date:  2016-08-16       Impact factor: 4.294

Review 9.  Rescuing mitochondria in traumatic brain injury and intracerebral hemorrhages - A potential therapeutic approach.

Authors:  Meenakshi Ahluwalia; Manish Kumar; Pankaj Ahluwalia; Scott Rahimi; John R Vender; Raghavan P Raju; David C Hess; Babak Baban; Fernando L Vale; Krishnan M Dhandapani; Kumar Vaibhav
Journal:  Neurochem Int       Date:  2021-09-22       Impact factor: 3.921

10.  Cyclooxygenase-2 mediates microglial activation and secondary dopaminergic cell death in the mouse MPTP model of Parkinson's disease.

Authors:  Rattanavijit Vijitruth; Mei Liu; Dong-Young Choi; Xuan V Nguyen; Randy L Hunter; Guoying Bing
Journal:  J Neuroinflammation       Date:  2006-03-27       Impact factor: 8.322
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