OBJECTIVES: to determine whether application of fibrin glue before closure of inguinal wounds reduces the incidence of lymphatic complications. DESIGN: we a prospective randomised trial. MATERIALS AND METHODS: 224 consecutive patients were enrolled. The wounds were randomly assigned to standard closure (group A, n = 134) or closure with application of fibrin glue (group B, n = 132). The incidence of local lymphatic and non-lymphatic complications, the amount of lymphatic fluid collected, and the time to drain removal were compared in the groups. RESULTS: the incidence of lymphatic complications was 19% in group A and 10% in group B (p = 0.027). The average drain output and the time to drain removal did not differ in the two groups. The total incidence of non-lymphatic local complications was 10% and did not differ in the two groups. CONCLUSIONS:fibrin glue application is associated with a significant reduction in lymphatic complications.
RCT Entities:
OBJECTIVES: to determine whether application of fibrin glue before closure of inguinal wounds reduces the incidence of lymphatic complications. DESIGN: we a prospective randomised trial. MATERIALS AND METHODS: 224 consecutive patients were enrolled. The wounds were randomly assigned to standard closure (group A, n = 134) or closure with application of fibrin glue (group B, n = 132). The incidence of local lymphatic and non-lymphatic complications, the amount of lymphatic fluid collected, and the time to drain removal were compared in the groups. RESULTS: the incidence of lymphatic complications was 19% in group A and 10% in group B (p = 0.027). The average drain output and the time to drain removal did not differ in the two groups. The total incidence of non-lymphatic local complications was 10% and did not differ in the two groups. CONCLUSIONS: fibrin glue application is associated with a significant reduction in lymphatic complications.
Authors: Andrzej Obara; Miroslaw A Dziekiewicz; Marek Maruszynski; Adam Witkowski; Maciej Dąbrowski; Zbigniew Chmielak Journal: Wideochir Inne Tech Maloinwazyjne Date: 2014-05-26 Impact factor: 1.195
Authors: Sebastian P Pleger; Nadine Nink; Meshal Elzien; Alexander Kunold; Ahmed Koshty; Andreas Böning Journal: Int Wound J Date: 2017-10-25 Impact factor: 3.315
Authors: Andreas Lutz Heinrich Gerken; Florian Herrle; Jens Jakob; Christel Weiß; Nuh N Rahbari; Kai Nowak; Constantin Karthein; Peter Hohenberger; Jürgen Weitz; Christoph Reißfelder; Jakob C Dobroschke Journal: Langenbecks Arch Surg Date: 2020-08-20 Impact factor: 3.445