| Literature DB >> 12217040 |
Katrin Gisselfält1, Bengt Edberg, Per Flodin.
Abstract
In the present study we describe the synthesis, wet spinning, mechanical testing, and degradation of poly(urethane urea)s (PUURs) intended for clinical use in anterior cruciate ligament (ACL) reconstruction. The effects of soft segment chemical composition and molar mass and the kind of diamine chain extender on the material properties were investigated. It was found that the fibers made of PUUR with polycaprolactone diol (PCL530) as soft segment and MDI/1,3-DAP as hard segment (PCL530-3) have high tensile strength and high modulus and when degraded keep their tensile strength for the time demanded for the application. In conclusion, from a chemical and mechanical point of view PUUR fibers of PCL530-3, ARTELON, are suitable for designing a degradable ACL device.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12217040 DOI： 10.1021/bm025535u
Source DB: PubMed Journal: Biomacromolecules ISSN： 1525-7797 Impact factor: 6.988