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Literature DB >> 12215721

Proven and potential clinical applications of mifpristone (RU486).

Irving M Spitz¹.

Abstract

Entities: Chemical

Mesh：

Substances：
Mifepristone

Year: 2002 PMID： 12215721 DOI： 10.1023/a:1020032711706

Source DB: PubMed Journal: Rev Endocr Metab Disord ISSN： 1389-9155 Impact factor: 6.514

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70 in total

1. Long-term mifepristone (RU486) therapy resulting in massive benign endometrial hyperplasia.

Authors: R S Newfield; I M Spitz; C Isacson; M I New
Journal: Clin Endocrinol (Oxf) Date: 2001-03 Impact factor: 3.478

2. The use of mifepristone prior to prostaglandin-induced mid-trimester abortion.

Authors: D R Urquhart; A A Templeton
Journal: Hum Reprod Date: 1990-10 Impact factor: 6.918

3. The placental transfer of mifepristone (RU 486) during the second trimester and its influence upon maternal and fetal steroid concentrations.

Authors: N C Hill; M Selinger; J Ferguson; I Z MacKenzie
Journal: Br J Obstet Gynaecol Date: 1990-05

Review 4. The use of progesterone antagonists and progesterone receptor modulators in contraception.

Authors: I M Spitz; P F Van Look; H J Coelingh Bennink
Journal: Steroids Date: 2000 Oct-Nov Impact factor: 2.668

Review 5. Progesterone antagonists and progesterone receptor modulators in the treatment of breast cancer.

Authors: J G Klijn; B Setyono-Han; J A Foekens
Journal: Steroids Date: 2000 Oct-Nov Impact factor: 2.668

6. Once-a-month treatment with a combination of mifepristone and the prostaglandin analogue misoprostol.

Authors: M L Swahn; M Bygdeman; J K Chen; K Gemzell-Danielsson; S Song; Q Y Yang; P J Yang; M L Qian; W F Chang
Journal: Hum Reprod Date: 1999-02 Impact factor: 6.918

7. Efficacy of mifepristone followed on the same day by misoprostol for early termination of pregnancy: report of a randomised trial.

Authors: M D Creinin; J L Schwartz; H C Pymar; W Fink
Journal: BJOG Date: 2001-05 Impact factor: 6.531

Proven and potential clinical applications of mifpristone (RU486).

1. Long-term mifepristone (RU486) therapy resulting in massive benign endometrial hyperplasia.

2. The use of mifepristone prior to prostaglandin-induced mid-trimester abortion.

3. The placental transfer of mifepristone (RU 486) during the second trimester and its influence upon maternal and fetal steroid concentrations.

Review 4. The use of progesterone antagonists and progesterone receptor modulators in contraception.

Review 5. Progesterone antagonists and progesterone receptor modulators in the treatment of breast cancer.

6. Once-a-month treatment with a combination of mifepristone and the prostaglandin analogue misoprostol.

7. Efficacy of mifepristone followed on the same day by misoprostol for early termination of pregnancy: report of a randomised trial.

8. Effects of daily low dose mifepristone on endometrial maturation and proliferation.

Review 9. RU486: pharmacology and potential use in the treatment of endometriosis and leiomyomata uteri.

10. Termination of early pregnancy by the progesterone antagonist RU 486 (Mifepristone).

1. The steroid RU486 induces UCP1 expression in brown adipocytes.