Literature DB >> 12215133

Impact of over-the-counter sales on effectiveness of pharmaceutical aids for smoking cessation.

John P Pierce1, Elizabeth A Gilpin.   

Abstract

CONTEXT: Successful smoking cessation is a major public health goal. In controlled clinical trials, nicotine replacement therapy (NRT) and the antidepressant bupropion have been shown to significantly increase cessation rates only for moderate to heavy smokers (> or = 15 cigarettes/d). Nicotine replacement therapy is heavily promoted to the general population by both the pharmaceutical industry and tobacco control advocates.
OBJECTIVE: To examine trends in smoking cessation, pharmaceutical cessation aid use, and success in cessation in the general California population. DESIGN, SETTING, AND PARTICIPANTS: The large population-based California Tobacco Surveys of 1992, 1996, and 1999, including 5247 (71.3% response rate), 9725 (72.9% response rate), and 6412 (68.4% response rate) respondents, respectively. MAIN OUTCOME MEASURES: Rates of cessation attempts (> or = 1 day) among smokers in the last year, use of pharmaceutical aids (mostly over-the-counter products since 1996), and cessation success.
RESULTS: Between 1992 and 1999, cessation attempts among California smokers increased 61.4% (from 38.1% to 61.5%), and NRT use among quitters increased 50.5% (from 9.3% to 14.0%). A total of 17.2% of quitters used NRT, an antidepressant, or both as an aid to cessation in 1999. In 1996 and 1999, the median duration of aid use (14 days) was much less than recommended, and only about 20% of users had adjuvant one-on-one or group behavioral counseling. Use of NRT increased short-term cessation success in moderate to heavy smokers in each survey year. However, a long-term cessation advantage was only observed before NRT became widely available over-the-counter (August 1996). In 1999, no advantage for pharmaceutical aid users was observed in either the short or long term for the nearly 60% of California smokers classified as light smokers (<15 cigarettes/d).
CONCLUSION: Since becoming available over the counter, NRT appears no longer effective in increasing long-term successful cessation in California smokers.

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Year:  2002        PMID: 12215133     DOI: 10.1001/jama.288.10.1260

Source DB:  PubMed          Journal:  JAMA        ISSN: 0098-7484            Impact factor:   56.272


  72 in total

Review 1.  A meta-analysis of the efficacy of over-the-counter nicotine replacement.

Authors:  J R Hughes; S Shiffman; P Callas; J Zhang
Journal:  Tob Control       Date:  2003-03       Impact factor: 7.552

2.  Estimating the health consequences of replacing cigarettes with nicotine inhalers.

Authors:  W Sumner
Journal:  Tob Control       Date:  2003-06       Impact factor: 7.552

3.  Persistent use of nicotine replacement therapy: an analysis of actual purchase patterns in a population based sample.

Authors:  S Shiffman; J R Hughes; J L Pillitteri; S L Burton
Journal:  Tob Control       Date:  2003-09       Impact factor: 7.552

4.  Systematic biases in cross-sectional community studies may underestimate the effectiveness of stop-smoking medications.

Authors:  Ron Borland; Timea R Partos; K Michael Cummings
Journal:  Nicotine Tob Res       Date:  2012-02-07       Impact factor: 4.244

5.  Enhancing dissemination of smoking cessation quitlines through T2 translational research: a unique partnership to address disparities in the delivery of effective cessation treatment.

Authors:  Jennifer Irvin Vidrine; Vance Rabius; Margo Hilliard Alford; Yisheng Li; David W Wetter
Journal:  J Public Health Manag Pract       Date:  2010 Jul-Aug

6.  Adherence to and reasons for premature discontinuation from stop-smoking medications: data from the ITC Four-Country Survey.

Authors:  James Balmford; Ron Borland; David Hammond; K Michael Cummings
Journal:  Nicotine Tob Res       Date:  2010-12-08       Impact factor: 4.244

7.  Modeling the impact of smoking-cessation treatment policies on quit rates.

Authors:  David T Levy; Amanda L Graham; Patricia L Mabry; David B Abrams; C Tracy Orleans
Journal:  Am J Prev Med       Date:  2010-03       Impact factor: 5.043

8.  Is nicotine replacement therapy for smoking cessation effective in the "real world"? Findings from a prospective multinational cohort study.

Authors:  Robert West; Xiaolei Zhou
Journal:  Thorax       Date:  2007-06-15       Impact factor: 9.139

Review 9.  Over-the-counter nicotine replacement therapy: can its impact on smoking cessation be enhanced?

Authors:  Nancy Amodei; R J Lamb
Journal:  Psychol Addict Behav       Date:  2008-12

10.  Nicotine patch vs. nicotine lozenge for smoking cessation: an effectiveness trial coordinated by the Community Clinical Oncology Program.

Authors:  Robert A Schnoll; Elisa Martinez; Kristina L Tatum; Marcella Glass; Albert Bernath; Daron Ferris; Patrick Reynolds
Journal:  Drug Alcohol Depend       Date:  2009-12-09       Impact factor: 4.492

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