Literature DB >> 12214852

Anti-human immunodeficiency virus-type 1 activity of constituents from Juglans mandshurica.

Byung Sun Min1, Hyeong Kyu Lee, Sang Myung Lee, Young Ho Kim, Ki Hwan Bae, Toru Otake, Norio Nakamura, Masao Hattori.   

Abstract

Three naphthalene glycosides (1-3), four flavonoids (4-7), and two galloyl glycosides (8-9) were isolated from the stem-bark of Juglans mandshurica (Juglandaceae). Their structures were determined by chemical and spectral means, including to 2D-NMR (COSY, HMQC, and HMBC) experiments. Amongst the isolated compounds, taxifolin (4) showed the most potent HIV-induced cytopethic activity against MT-4 cells with complete inhibitory concentration (IC100) value of 25 microg/ml and maximum cytotoxic concentration (CC100) value of above 100 microg/ml. However, naphthalene glycosides (1-3), flavonoids (5-7), and galloyl tannins (8-9) were inactive against anti-HIV-1 activity.

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Year:  2002        PMID： 12214852     DOI： 10.1007/BF02976598

Source DB:  PubMed          Journal:  Arch Pharm Res        ISSN： 0253-6269            Impact factor:   4.946


  6 in total

1.  Novel Ionophores Active against La Crosse Virus Identified through Rapid Antiviral Screening.

Authors:  Zachary J Sandler; Mason R Firpo; Oreoluwa S Omoba; Michelle N Vu; Vineet D Menachery; Bryan C Mounce
Journal:  Antimicrob Agents Chemother       Date:  2020-05-21       Impact factor: 5.191

Review 2.  Structure-Activity-Relationship and Mechanistic Insights for Anti-HIV Natural Products.

Authors:  Ramandeep Kaur; Pooja Sharma; Girish K Gupta; Fidele Ntie-Kang; Dinesh Kumar
Journal:  Molecules       Date:  2020-04-29       Impact factor: 4.411

Review 3.  Juglans mandshurica Maxim.: A Review of Its Traditional Usages, Phytochemical Constituents, and Pharmacological Properties.

Authors:  Fei Luan; Ziyan Wang; Yan Yang; Yafei Ji; Haizhen Lv; Keqing Han; Daoheng Liu; Xiaofei Shang; Xirui He; Nan Zeng
Journal:  Front Pharmacol       Date:  2021-01-21       Impact factor: 5.810

4.  Active Components from Cassia abbreviata Prevent HIV-1 Entry by Distinct Mechanisms of Action.

Authors:  Yue Zheng; Xian-Wen Yang; Dominique Schols; Mattia Mori; Bruno Botta; Andy Chevigné; Martin Mulinge; André Steinmetz; Jean-Claude Schmit; Carole Seguin-Devaux
Journal:  Int J Mol Sci       Date:  2021-05-10       Impact factor: 5.923

Review 5.  Medicinal Plants Used in the Treatment of Human Immunodeficiency Virus.

Authors:  Bahare Salehi; Nanjangud V Anil Kumar; Bilge Şener; Mehdi Sharifi-Rad; Mehtap Kılıç; Gail B Mahady; Sanja Vlaisavljevic; Marcello Iriti; Farzad Kobarfard; William N Setzer; Seyed Abdulmajid Ayatollahi; Athar Ata; Javad Sharifi-Rad
Journal:  Int J Mol Sci       Date:  2018-05-14       Impact factor: 5.923

6.  Identification of Polar Constituents in the Decoction of Juglans mandshurica and in the Medicated Egg Prepared with the Decoction by HPLC-Q-TOF MS².

Authors:  Tian-Min Wang; Ying Fu; Wen-Jie Yu; Chen Chen; Xue Di; Hui Zhang; Yan-Jun Zhai; Zheng-Yun Chu; Ting-Guo Kang; Hu-Biao Chen
Journal:  Molecules       Date:  2017-09-01       Impact factor: 4.411
  6 in total

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