OBJECTIVE: The authors report results from a 7-year prospective study of depression and mortality in 2,558 Medicare recipients age 65 and older. METHODS: This report is based on a secondary data analysis of a randomized controlled trial that evaluated the cost-effectiveness of preventive services for older enrollees in an HMO. RESULTS: Subjects with mild-to-moderate depression at baseline did not have an increased risk of mortality compared with those without significant depression. The 3% of older adults with the most severe depressive syndromes, however, had significant increases in mortality, even after adjusting for demographics, health risk behaviors, and chronic medical disorders. CONCLUSION: The increase in mortality in this group of older adults was comparable to that in participants with chronic medical disorders such as emphysema or heart disease.
RCT Entities:
OBJECTIVE: The authors report results from a 7-year prospective study of depression and mortality in 2,558 Medicare recipients age 65 and older. METHODS: This report is based on a secondary data analysis of a randomized controlled trial that evaluated the cost-effectiveness of preventive services for older enrollees in an HMO. RESULTS: Subjects with mild-to-moderate depression at baseline did not have an increased risk of mortality compared with those without significant depression. The 3% of older adults with the most severe depressive syndromes, however, had significant increases in mortality, even after adjusting for demographics, health risk behaviors, and chronic medical disorders. CONCLUSION: The increase in mortality in this group of older adults was comparable to that in participants with chronic medical disorders such as emphysema or heart disease.
Authors: Lisa C Barry; Roland J Thorpe; Brenda W J H Penninx; Kristine Yaffe; Dorothy Wakefield; Hilsa N Ayonayon; Suzanne Satterfield; Anne B Newman; Eleanor M Simonsick Journal: Am J Geriatr Psychiatry Date: 2013-10-11 Impact factor: 4.105
Authors: Patricia A Areán; Patrick J Raue; Charles McCulloch; Dora Kanellopoulos; Joanna K Seirup; Samprit Banerjee; Dimitris N Kiosses; Eleanor Dwyer; George S Alexopoulos Journal: Am J Geriatr Psychiatry Date: 2015-04-24 Impact factor: 4.105