Literature DB >> 12213051

Purine and pyrimidine (P2) receptors as drug targets.

Kenneth A Jacobson1, Michael F Jarvis, Michael Williams.   

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Year:  2002        PMID: 12213051     DOI: 10.1021/jm020046y

Source DB:  PubMed          Journal:  J Med Chem        ISSN: 0022-2623            Impact factor:   7.446


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  93 in total

1.  Extracellular nucleotides induce vasodilatation in human arteries via prostaglandins, nitric oxide and endothelium-derived hyperpolarising factor.

Authors:  Anna-Karin Wihlborg; Malin Malmsjö; Atli Eyjolfsson; Ronny Gustafsson; Kenneth Jacobson; David Erlinge
Journal:  Br J Pharmacol       Date:  2003-04       Impact factor: 8.739

2.  2', 3'-O-(2,4,6,trinitrophenyl)-ATP and A-317491 are competitive antagonists at a slowly desensitizing chimeric human P2X3 receptor.

Authors:  Torben R Neelands; Edward C Burgard; Marie E Uchic; Heath A McDonald; Wende Niforatos; Connie R Faltynek; Kevin J Lynch; Michael F Jarvis
Journal:  Br J Pharmacol       Date:  2003-07-29       Impact factor: 8.739

3.  Methylene ATP analogs as modulators of extracellular ATP metabolism and accumulation.

Authors:  Sheldon M Joseph; Matthew A Pifer; Ronald J Przybylski; George R Dubyak
Journal:  Br J Pharmacol       Date:  2004-06-21       Impact factor: 8.739

Review 4.  Molecular recognition at purine and pyrimidine nucleotide (P2) receptors.

Authors:  Kenneth A Jacobson; Stefano Costanzi; Michihiro Ohno; Bhalchandra V Joshi; Pedro Besada; Bin Xu; Susanna Tchilibon
Journal:  Curr Top Med Chem       Date:  2004       Impact factor: 3.295

5.  P2X receptor antagonists for pain management: examination of binding and physicochemical properties.

Authors:  Rebecca J Gum; Brian Wakefield; Michael F Jarvis
Journal:  Purinergic Signal       Date:  2011-11-16       Impact factor: 3.765

6.  Development of a comprehensive set of P2 receptor pharmacological research compounds.

Authors:  R A Felix; S Martin; S Pinion; D J Crawford
Journal:  Purinergic Signal       Date:  2011-11-04       Impact factor: 3.765

7.  ATP-mediated potassium recycling in the cochlear supporting cells.

Authors:  Yan Zhu; Hong-Bo Zhao
Journal:  Purinergic Signal       Date:  2010-05-18       Impact factor: 3.765

8.  Architecture of P2Y nucleotide receptors: structural comparison based on sequence analysis, mutagenesis, and homology modeling.

Authors:  Stefano Costanzi; Liaman Mamedova; Zhan-Guo Gao; Kenneth A Jacobson
Journal:  J Med Chem       Date:  2004-10-21       Impact factor: 7.446

9.  Diisothiocyanate derivatives as potent, insurmountable antagonists of P2Y6 nucleotide receptors.

Authors:  Liaman K Mamedova; Bhalchandra V Joshi; Zhan-Guo Gao; Ivar von Kügelgen; Kenneth A Jacobson
Journal:  Biochem Pharmacol       Date:  2004-05-01       Impact factor: 5.858

10.  Effects of the allosteric modulator SCH-202676 on adenosine and P2Y receptors.

Authors:  Zhan-Guo Gao; Ariel S Gross; Kenneth A Jacobson
Journal:  Life Sci       Date:  2004-05-07       Impact factor: 5.037

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