Literature DB >> 12211023

Structure of 2C-methyl-D-erythrol-2,4-cyclodiphosphate synthase from Haemophilus influenzae: activation by conformational transition.

Christopher Lehmann1, Kap Lim, John Toedt, Wojciech Krajewski, Andrew Howard, Edward Eisenstein, Osnat Herzberg.   

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Year:  2002        PMID： 12211023     DOI： 10.1002/prot.10182

Source DB:  PubMed          Journal:  Proteins        ISSN： 0887-3585


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  8 in total

Review 1.  The Mycobacterium tuberculosis MEP (2C-methyl-d-erythritol 4-phosphate) pathway as a new drug target.

Authors:  Hyungjin Eoh; Patrick J Brennan; Dean C Crick
Journal:  Tuberculosis (Edinb)       Date:  2008-09-14       Impact factor: 3.131

2.  Synthesis of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate and kinetic studies of Mycobacterium tuberculosis IspF.

Authors:  Prabagaran Narayanasamy; Hyungjin Eoh; Patrick J Brennan; Dean C Crick
Journal:  Chem Biol       Date:  2010-02-26

Review 3.  Biochemistry of the non-mevalonate isoprenoid pathway.

Authors:  Tobias Gräwert; Michael Groll; Felix Rohdich; Adelbert Bacher; Wolfgang Eisenreich
Journal:  Cell Mol Life Sci       Date:  2011-07-09       Impact factor: 9.261

4.  Biosynthesis of isoprenoids in plants: structure of the 2C-methyl-D-erithrytol 2,4-cyclodiphosphate synthase from Arabidopsis thaliana. Comparison with the bacterial enzymes.

Authors:  Barbara M Calisto; Jordi Perez-Gil; Maria Bergua; Jordi Querol-Audi; Ignacio Fita; Santiago Imperial
Journal:  Protein Sci       Date:  2007-07-27       Impact factor: 6.725

5.  The structure of Mycobacteria 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase, an essential enzyme, provides a platform for drug discovery.

Authors:  Lori Buetow; Amanda C Brown; Tanya Parish; William N Hunter
Journal:  BMC Struct Biol       Date:  2007-10-23

6.  A structure-based approach to ligand discovery for 2C-methyl-D-erythritol-2,4-cyclodiphosphate synthase: a target for antimicrobial therapy.

Authors:  Nicola L Ramsden; Lori Buetow; Alice Dawson; Lauris A Kemp; Venkatsubramanian Ulaganathan; Ruth Brenk; Gerhard Klebe; William N Hunter
Journal:  J Med Chem       Date:  2009-04-23       Impact factor: 7.446

Review 7.  New Insight into Isoprenoids Biosynthesis Process and Future Prospects for Drug Designing in Plasmodium.

Authors:  Gagandeep S Saggu; Zarna R Pala; Shilpi Garg; Vishal Saxena
Journal:  Front Microbiol       Date:  2016-09-13       Impact factor: 5.640

8.  Crystal structure of IspF from Bacillus subtilis and absence of protein complex assembly amongst IspD/IspE/IspF enzymes in the MEP pathway.

Authors:  Zhongchuan Liu; Yun Jin; Weifeng Liu; Yong Tao; Ganggang Wang
Journal:  Biosci Rep       Date:  2018-02-21       Impact factor: 3.840
  8 in total

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