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Literature DB >> 12208987

Detection and analysis of hepatitis C virus sequences in cerebrospinal fluid.

Tomasz Laskus¹, Marek Radkowski, Agnieszka Bednarska, Jeffrey Wilkinson, Debra Adair, Marek Nowicki, Georgia B Nikolopoulou, Hugo Vargas, Jorge Rakela.

Abstract

Hepatitis C virus (HCV) sequences were detected in cerebrospinal fluid (CSF) in 8 of 13 HCV-positive patients. In four patients harboring different virus strains in serum and peripheral blood mononuclear cells (PBMC), CSF-derived virus was similar to that found in PBMC, which suggests that PBMC could carry HCV into the brain.

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Year: 2002 PMID： 12208987 PMCID： PMC136534 DOI： 10.1128/jvi.76.19.10064-10068.2002

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

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