Literature DB >> 12207552

Relapse prevention and maintaining abstinence in older adults with alcohol-use disorders.

Christopher Barrick1, Gerard J Connors.   

Abstract

Although older adults are sometimes believed to have the lowest rates of alcohol abuse as an age cohort, the prevalence of alcohol use and abuse in this group is clearly underestimated. The under-diagnosis of alcohol abuse is due, in part, to the facts that the effects of alcohol use among older adults tend to be less clearly visible than among other age groups and that older adults are less likely to seek treatment than younger age groups. An additional challenge to diagnosis may be a lack of previous alcohol abuse by the patient, as approximately one-third of older adults with alcohol-use problems first develop their drinking problem after the age of 60 years. With a demographic shift that is expected to increase the number of older adults with alcohol problems, the awareness and understanding of this problem becomes increasingly important. Under-diagnosis of problem drinking in older adults is particularly unfortunate because the risks associated with alcohol abuse and relapse for the elderly are significant. Relapse, or the return to drinking following abstinence, may follow situations that are of particularly high risk for older adults. These include situations related to anxiety, interpersonal conflict, depression, loneliness, loss or social isolation. By helping patients to monitor these high-risk situations, to identify strategies that have been successful in promoting abstinence in the past, and to become engaged in treatment, relapse may be avoided and abstinence maintained. Treatments such as cognitive-behavioural therapy, group and family therapies and self-help groups are just as effective for older adults as they are for other age groups. In fact, group and family therapies and self-help groups may be of particular benefit to older adults because of the emphasis on social support. Medicinal adjuncts are also equally effective in the elderly, but strict compliance and careful monitoring of adverse effects are especially important in patients who take multiple medications. Because of their benign adverse effect profiles, naltrexone and acamprosate are particularly good pharmacological agents for relapse prevention in older adults.

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Year:  2002        PMID: 12207552     DOI: 10.2165/00002512-200219080-00004

Source DB:  PubMed          Journal:  Drugs Aging        ISSN: 1170-229X            Impact factor:   3.923


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Review 1.  Drug therapy for alcohol dependence.

Authors:  R M Swift
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Review 2.  Pharmacotherapy of alcoholism: gaps in knowledge and opportunities for research.

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3.  Pharmacological treatment of alcohol dependence: a review of the evidence.

Authors:  J C Garbutt; S L West; T S Carey; K N Lohr; F T Crews
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4.  Self-efficacy: toward a unifying theory of behavioral change.

Authors:  A Bandura
Journal:  Psychol Rev       Date:  1977-03       Impact factor: 8.934

5.  Acamprosate appears to decrease alcohol intake in weaned alcoholics.

Authors:  J P Lhuintre; N Moore; G Tran; L Steru; S Langrenon; M Daoust; P Parot; P Ladure; C Libert; F Boismare
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6.  Acamprosate and relapse prevention in the treatment of alcohol dependence: a placebo-controlled study.

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7.  Effect of naltrexone on subjective alcohol response in subjects at high and low risk for future alcohol dependence.

Authors:  A C King; J R Volpicelli; A Frazer; C P O'Brien
Journal:  Psychopharmacology (Berl)       Date:  1997-01       Impact factor: 4.530

8.  Disulfiram treatment of alcoholism. A Veterans Administration cooperative study.

Authors:  R K Fuller; L Branchey; D R Brightwell; R M Derman; C D Emrick; F L Iber; K E James; R B Lacoursiere; K K Lee; I Lowenstam
Journal:  JAMA       Date:  1986-09-19       Impact factor: 56.272

Review 9.  Alcoholism in older persons: a review of the literature.

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