| Literature DB >> 12206553 |
Gijs J Nollen1, Maarten Groenink, Ernst E van der Wall, Barbara J M Mulder.
Abstract
Marfan's syndrome is an inherited disorder of connective tissue, caused by mutations in the fibrillin-1 gene located on chromosome 15. Diagnosis is still based on a combination of major and minor clinical features. Prognosis is mainly determined by the cardiovascular complications. Advances in surgical and medical treatment for these complications have dramatically improved the prognosis of the syndrome.Entities:
Mesh：
Year: 2002 PMID： 12206553 DOI： 10.1017/s1047951100012907
Source DB: PubMed Journal: Cardiol Young ISSN： 1047-9511 Impact factor: 1.093