Literature DB >> 12205815

[Role of gastroesophageal reflux in asthma in infants and young children].

L Donato1, A Livolsi, C Gaugler, B Escande, L Weiss, A Ducoloné.   

Abstract

Gastroesophageal reflux (GER) occurs more frequently in asthmatic children than in general population. Esophageal pH recording data may be somewhat particular. The debate on GER increasing bronchial obstruction or GER being a parallel phenomenon remains controversial. Hypotheses are: acid microaspirations giving bronchospasm, vagally-transmitted reflex, or more probably coexisting phenomena. Pulmonary contamination is rarely seen during esophageal scintigraphy. Asthma symptoms are rarely clearly correlated to acid reflux episodes in pH-recording studies. However the esophageal acid infusion test may increase bronchial obstruction in adult asthmatics. Basically, when should one seek GER in asthmatic children? Many authors keep this for asthmatic children not responding to conventional treatment, also keeping in mind that GER-specific therapy efficacy is often difficult to appreciate in such patients. Briefly, one may speculate that GER improves with bronchodilator treatment in most cases.

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Year:  2002        PMID: 12205815     DOI: 10.1016/s0929-693x(02)00150-1

Source DB:  PubMed          Journal:  Arch Pediatr        ISSN: 0929-693X            Impact factor:   1.180


  1 in total

Review 1.  Gastro-oesophageal reflux and bronchial asthma: current status and future directions.

Authors:  J L Mathew; M Singh; S K Mittal
Journal:  Postgrad Med J       Date:  2004-12       Impact factor: 2.401

  1 in total

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