Literature DB >> 1220558

Correlation of serum aspirin esterase activity and half-life of salicylic acid.

K Trnavský, M Zachar.   

Abstract

An inverse correlation was found between the serum aspirin esterase activity in human subjects and the biological half-life of salicylic acid in serum and a direct relationship between the values of the elimination rate constant and the activity of this enzyme. The rate of acetylsalicylic acid breakdown may be one of the factors which influences the biological half-life of salicylates in the organism and may participate also in determining the individual response to the administered drug.

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Year:  1975        PMID： 1220558     DOI： 10.1007/bf01972693

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  7 in total

1.  VARIATION IN RATE OF SALICYLATE ELIMINATION BY HUMANS.

Authors:  G LEVY; L E HOLLISTER
Journal:  Br Med J       Date:  1964-08-01

2.  SITE OF ACTION OF NARCOTIC AND NON-NARCOTIC ANALGESICS DETERMINED BY BLOCKING BRADYKININ-EVOKED VISCERAL PAIN.

Authors:  R K LIM; F GUZMAN; D W RODGERS; K GOTO; C BRAUN; G D DICKERSON; R J ENGLE
Journal:  Arch Int Pharmacodyn Ther       Date:  1964-11-01

3.  Evidence for a sex-linked difference in aspirin metabolism.

Authors:  R Menguy; L Desbaillets; Y F Masters; S Okabe
Journal:  Nature       Date:  1972-09-08       Impact factor: 49.962

4.  Abnormal aspirin metabolism in patients with cirrhosis and its possible relationship to bleeding in cirrhotics.

Authors:  R Menguy; L Desbaillets; S Okabe; Y F Masters
Journal:  Ann Surg       Date:  1972-09       Impact factor: 12.969

5.  The influence of age on the activity of acetylsalicylic acid-esterase and protein-salicylate binding.

Authors:  A Windorfer; W Kuenzer; R Urbanek
Journal:  Eur J Clin Pharmacol       Date:  1974       Impact factor: 2.953

6.  Absorption kinetics of aspirin in man following oral administration of an aqueous solution.

Authors:  M Rowland; S Riegelman; P A Harris; S D Sholkoff
Journal:  J Pharm Sci       Date:  1972-03       Impact factor: 3.534

7.  Presence of acetylsalicylic acid in plasma following oral ingestion of aspirin.

Authors:  J R LEONARDS
Journal:  Proc Soc Exp Biol Med       Date:  1962-06
  7 in total
  6 in total

1.  Comparative pharmacokinetics of salicylate in camels, sheep and goats.

Authors:  B H Ali
Journal:  Eur J Drug Metab Pharmacokinet       Date:  2003 Apr-Jun       Impact factor: 2.441

2.  Aromatic hydroxylation of salicylic acid and aspirin by human cytochromes P450.

Authors:  Mirza Bojić; Carl A Sedgeman; Leslie D Nagy; F Peter Guengerich
Journal:  Eur J Pharm Sci       Date:  2015-03-31       Impact factor: 4.384

Review 3.  Clinical significance of esterases in man.

Authors:  F M Williams
Journal:  Clin Pharmacokinet       Date:  1985 Sep-Oct       Impact factor: 6.447

4.  The Use of Gene Ontology Term and KEGG Pathway Enrichment for Analysis of Drug Half-Life.

Authors:  Yu-Hang Zhang; Chen Chu; Shaopeng Wang; Lei Chen; Jing Lu; XiangYin Kong; Tao Huang; HaiPeng Li; Yu-Dong Cai
Journal:  PLoS One       Date:  2016-10-25       Impact factor: 3.240

Review 5.  Aspirin for Prevention of Preeclampsia.

Authors:  A Atallah; E Lecarpentier; F Goffinet; M Doret-Dion; P Gaucherand; V Tsatsaris
Journal:  Drugs       Date:  2017-11       Impact factor: 9.546

6.  Sodium salicylate and 5-aminosalicylic acid synergistically inhibit the growth of human colon cancer cells and mouse intestinal polyp-derived cells.

Authors:  Hideki Takakura; Mano Horinaka; Ayaka Imai; Yuichi Aono; Toshimasa Nakao; Shingo Miyamoto; Yosuke Iizumi; Motoki Watanabe; Takumi Narita; Hideki Ishikawa; Michihiro Mutoh; Toshiyuki Sakai
Journal:  J Clin Biochem Nutr       Date:  2021-12-18       Impact factor: 3.114
  6 in total

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