| Literature DB >> 12205443 |
Jennifer LeCouter1, Rui Lin, Napoleone Ferrara.
Abstract
The diversity in growth and morphological characteristics among endothelial cells in different normal tissues and tumors has been long recognized. Yet there has been no clear molecular explanation for such diversity at the level of vascular endothelial growth factor A (VEGF-A) and other established regulators of angiogenesis that are expressed widely and show little tissue selectivity in their angiogenic properties. Endocrine gland-derived VEGF represents the first example of a tissue-specific angiogenic factor, likely to be followed by others.Entities:
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Year: 2002 PMID： 12205443 DOI： 10.1038/nm0902-913
Source DB: PubMed Journal: Nat Med ISSN： 1078-8956 Impact factor: 53.440