| Literature DB >> 12205065 |
Dilek Colak1, Thierry Naas, Filiz Gunseren, Nicolas Fortineau, Dilara Ogunc, Meral Gultekin, Patrice Nordmann.
Abstract
Twenty multidrug-resistant vancomycin-resistant Enterococcus faecium strains of the VanA phenotype were isolated over a 1 year period from five patients in the intensive care unit at the University Hospital of Antalya, Turkey. Molecular investigation showed that these strains belonged to five different pulsotypes and that the vanA gene was carried by a Tn1546-like transposon inserted onto a self-transferable plasmid of approximately 200 kb. One patient was infected by two different strains, suggesting horizontal gene transfer within that patient. This is the first documented outbreak of VRE in Turkey with concomitant spread of plasmid and strains.Entities:
Mesh：
Substances：
Year: 2002 PMID： 12205065 DOI： 10.1093/jac/dkf134
Source DB: PubMed Journal: J Antimicrob Chemother ISSN： 0305-7453 Impact factor: 5.790