| Literature DB >> 1220424 |
Abstract
Carbamazepine is extracted with dichloromethane from whole blood. After a rinsing procedure the residue is gaschromatographed partly in methanol, where two peaks occur, and partly in a methylating reagent, where the same two peaks are seen, the heights of these now being reversed. This reversal is used as a means of identification. Recovery was found to be 94 +/- 12 %. Blood analysis from 12 patients being treated with carbamazepine gave values from 0.6 - 6.5 mg/kg.Entities:
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Year: 1975 PMID： 1220424 DOI： 10.1007/bf02114608
Source DB: PubMed Journal: Z Rechtsmed ISSN： 0044-3433