Literature DB >> 12203980

Site-directed mutagenesis of Tyr354 in Geobacillus stearothermophilus alanine racemase identifies a role in controlling substrate specificity and a possible role in the evolution of antibiotic resistance.

Wayne M Patrick1, Jan Weisner, Jonathan M Blackburn.   

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Year:  2002        PMID： 12203980     DOI： 10.1002/1439-7633(20020802)3:8<789::AID-CBIC789>3.0.CO;2-D

Source DB:  PubMed          Journal:  Chembiochem        ISSN： 1439-4227            Impact factor:   3.164


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  12 in total

Review 1.  Vancomycin resistance in enterococci due to synthesis of precursors terminating in D-alanyl-D-serine.

Authors:  Peter E Reynolds; Patrice Courvalin
Journal:  Antimicrob Agents Chemother       Date:  2005-01       Impact factor: 5.191

2.  A novel assay method for an amino acid racemase reaction based on circular dichroism.

Authors:  Masafumi Noda; Yasuyuki Matoba; Takanori Kumagai; Masanori Sugiyama
Journal:  Biochem J       Date:  2005-07-15       Impact factor: 3.857

3.  Residues Asp164 and Glu165 at the substrate entryway function potently in substrate orientation of alanine racemase from E. coli: Enzymatic characterization with crystal structure analysis.

Authors:  Dalei Wu; Tiancen Hu; Liang Zhang; Jing Chen; Jiamu Du; Jianping Ding; Hualiang Jiang; Xu Shen
Journal:  Protein Sci       Date:  2008-04-23       Impact factor: 6.725

Review 4.  Molecular mechanisms of vancomycin resistance.

Authors:  Peter J Stogios; Alexei Savchenko
Journal:  Protein Sci       Date:  2020-01-23       Impact factor: 6.725

5.  The crystal structure of alanine racemase from Streptococcus pneumoniae, a target for structure-based drug design.

Authors:  Hookang Im; Miriam L Sharpe; Ulrich Strych; Milya Davlieva; Kurt L Krause
Journal:  BMC Microbiol       Date:  2011-05-25       Impact factor: 3.605

6.  Structural features and kinetic characterization of alanine racemase from Staphylococcus aureus (Mu50).

Authors:  Emma R Scaletti; Sylvia R Luckner; Kurt L Krause
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2011-12-09

7.  Mechanistic and Evolutionary Insights from the Reciprocal Promiscuity of Two Pyridoxal Phosphate-dependent Enzymes.

Authors:  Valerie W C Soo; Yuliana Yosaatmadja; Christopher J Squire; Wayne M Patrick
Journal:  J Biol Chem       Date:  2016-07-29       Impact factor: 5.157

8.  Crystal structures of lysine-preferred racemases, the non-antibiotic selectable markers for transgenic plants.

Authors:  Hsin-Mao Wu; Yi-Chia Kuan; Chia-Han Chu; Wen-Hwei Hsu; Wen-Ching Wang
Journal:  PLoS One       Date:  2012-10-31       Impact factor: 3.240

9.  Crystal Structure of a Thermostable Alanine Racemase from Thermoanaerobacter tengcongensis MB4 Reveals the Role of Gln360 in Substrate Selection.

Authors:  Xiaoliang Sun; Guangzheng He; Xiaoyan Wang; Shujing Xu; Jiansong Ju; Xiaoling Xu
Journal:  PLoS One       Date:  2015-07-28       Impact factor: 3.240

10.  Structural and Functional Adaptation of Vancomycin Resistance VanT Serine Racemases.

Authors:  Djalal Meziane-Cherif; Peter J Stogios; Elena Evdokimova; Olga Egorova; Alexei Savchenko; Patrice Courvalin
Journal:  mBio       Date:  2015-08-11       Impact factor: 7.867
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