Literature DB >> 12202014

Alcohol use affects the outcome of treatment for cocaine abuse.

Matilda M Mengis1, Peg M Maude-Griffin, Kevin Delucchi, Sharon M Hall.   

Abstract

This study investigated whether alcohol use affects baseline characteristics and treatment outcome in 128 adults who participated in a randomized trial of cognitive behavioral vs. 12-step treatment for crack cocaine abuse. Assessments were taken at baseline and weeks 4, 8, 12, and 26 on biologically-verified cocaine abstinence and psychometric measures. Alcohol use was measured at intake and subsequent assessments using the Addiction Severity Index (ASI) and self-reported frequency of alcohol consumption. Results indicate alcohol use at baseline was associated with increased baseline cocaine use and ASI drug severity but was not associated with ASI psychiatric severity, psychiatric diagnoses, or other baseline variables. Alcohol use at baseline did not predict worse treatment outcome for cocaine abstinence. However, alcohol use after four weeks of treatment did predict ability to achieve cocaine abstinence at assessment points during and after treatment.

Entities:  

Mesh:

Year:  2002        PMID: 12202014     DOI: 10.1080/10550490290087992

Source DB:  PubMed          Journal:  Am J Addict        ISSN: 1055-0496


  7 in total

1.  A double blind, placebo-controlled trial that combines disulfiram and naltrexone for treating co-occurring cocaine and alcohol dependence.

Authors:  Helen M Pettinati; Kyle M Kampman; Kevin G Lynch; Hu Xie; Charles Dackis; Amanda R Rabinowitz; Charles P O'Brien
Journal:  Addict Behav       Date:  2007-11-17       Impact factor: 3.913

2.  Effects of daily treatment with citicoline: a double-blind, placebo-controlled study in cocaine-dependent volunteers.

Authors:  Stephanie C Licata; David M Penetar; Caitlin Ravichandran; John Rodolico; Christopher Palmer; Jeff Berko; Thomas Geaghan; Alison Looby; Erica Peters; Elizabeth Ryan; Perry F Renshaw; Scott E Lukas
Journal:  J Addict Med       Date:  2011-03       Impact factor: 3.702

3.  Twelve-step program attendance and polysubstance use: interplay of alcohol and illicit drug use.

Authors:  J Scott Tonigan; Gregory K Beatty
Journal:  J Stud Alcohol Drugs       Date:  2011-09       Impact factor: 2.582

4.  Concurrent alcohol dependence among methadone-maintained cocaine abusers is associated with greater abstinence.

Authors:  Shannon A Byrne; Nancy M Petry
Journal:  Exp Clin Psychopharmacol       Date:  2011-04       Impact factor: 3.157

5.  Gender differences with high-dose naltrexone in patients with co-occurring cocaine and alcohol dependence.

Authors:  Helen M Pettinati; Kyle M Kampman; Kevin G Lynch; Jesse J Suh; Charles A Dackis; David W Oslin; Charles P O'Brien
Journal:  J Subst Abuse Treat       Date:  2007-07-30

6.  Cocaine abusers with and without alcohol dependence respond equally well to contingency management treatments.

Authors:  Carla J Rash; Sheila M Alessi; Nancy M Petry
Journal:  Exp Clin Psychopharmacol       Date:  2008-08       Impact factor: 3.157

7.  Chronic poly-drug administration damages adult mouse brain neural stem cells.

Authors:  Erica L McGrath; Caitlin R Schlagal; Ibdanelo Cortez; Tiffany J Dunn; Junling Gao; Robert G Fox; Sonja J Stutz; Yong-Fang Kuo; Jonathan D Hommel; Kelly T Dineley; Kathryn A Cunningham; Bhupendra S Kaphalia; Ping Wu
Journal:  Brain Res       Date:  2019-08-29       Impact factor: 3.610

  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.