| Literature DB >> 12201787 |
Christophe Hardouin1, Eric Doris, Bernard Rousseau, Charles Mioskowski.
Abstract
Straightforward access to anhydrovinblastine starting from the parent alkaloid leurosine is reported. The key deoxygenation step was first optimized on a model substrate. However, applied to leurosine, only the low-valent Cp2TiCl gave satisfactory results.Entities:
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Year: 2002 PMID： 12201787 DOI： 10.1021/jo0202942
Source DB: PubMed Journal: J Org Chem ISSN： 0022-3263 Impact factor: 4.354