Literature DB >> 12200930

HeinzelCluster: accelerated reconstruction for FORE and OSEM3D.

S Vollmar1, C Michel, J T Treffert, D F Newport, M Casey, C Knöss, K Wienhard, X Liu, M Defrise, W D Heiss.   

Abstract

Using iterative three-dimensional (3D) reconstruction techniques for reconstruction of positron emission tomography (PET) is not feasible on most single-processor machines due to the excessive computing time needed, especially so for the large sinogram sizes of our high-resolution research tomograph (HRRT). In our first approach to speed up reconstruction time we transform the 3D scan into the format of a two-dimensional (2D) scan with sinograms that can be reconstructed independently using Fourier rebinning (FORE) and a fast 2D reconstruction method. On our dedicated reconstruction cluster (seven four-processor systems, Intel PIII@700 MHz, switched fast ethernet and Myrinet, Windows NT Server), we process these 2D sinograms in parallel. We have achieved a speedup > 23 using 26 processors and also compared results for different communication methods (RPC, Syngo, Myrinet GM). The other approach is to parallelize OSEM3D (implementation of C Michel), which has produced the best results for HRRT data so far and is more suitable for an adequate treatment of the sinogram gaps that result from the detector geometry of the HRRT. We have implemented two levels of parallelization for four dedicated cluster (a shared memory fine-grain level on each node utilizing all four processors and a coarse-grain level allowing for 15 nodes) reducing the time for one core iteration from over 7 h to about 35 min.

Mesh:

Year:  2002        PMID: 12200930     DOI: 10.1088/0031-9155/47/15/307

Source DB:  PubMed          Journal:  Phys Med Biol        ISSN: 0031-9155            Impact factor:   3.609


  12 in total

1.  Iterative reconstruction of Fourier-rebinned PET data using sinogram blurring function estimated from point source scans.

Authors:  Michel S Tohme; Jinyi Qi
Journal:  Med Phys       Date:  2010-10       Impact factor: 4.071

2.  Non-invasive Standardised Uptake Value for Verification of the Use of Previously Validated Reference Region for [18F]Flortaucipir and [18F]Florbetapir Brain PET Studies.

Authors:  Bart M de Vries; Tessa Timmers; Emma E Wolters; Rik Ossenkoppele; Sander C J Verfaillie; Robert C Schuit; Philip Scheltens; Wiesje M van der Flier; Albert D Windhorst; Bart N M van Berckel; Ronald Boellaard; Sandeep S V Golla
Journal:  Mol Imaging Biol       Date:  2021-01-14       Impact factor: 3.488

3.  Harmonisation of PET/CT contrast recovery performance for brain studies.

Authors:  E E Verwer; S S V Golla; A Kaalep; M Lubberink; F H P van Velden; V Bettinardi; M Yaqub; T Sera; S Rijnsdorp; A A Lammertsma; R Boellaard
Journal:  Eur J Nucl Med Mol Imaging       Date:  2021-01-31       Impact factor: 9.236

4.  Quantification of [18F]DPA-714 binding in the human brain: initial studies in healthy controls and Alzheimer's disease patients.

Authors:  Sandeep S V Golla; Ronald Boellaard; Vesa Oikonen; Anja Hoffmann; Bart N M van Berckel; Albert D Windhorst; Jere Virta; Merja Haaparanta-Solin; Pauliina Luoto; Nina Savisto; Olof Solin; Ray Valencia; Andrea Thiele; Jonas Eriksson; Robert C Schuit; Adriaan A Lammertsma; Juha O Rinne
Journal:  J Cereb Blood Flow Metab       Date:  2015-02-04       Impact factor: 6.200

5.  A novel partial volume correction method for accurate quantification of [18F] flortaucipir in the hippocampus.

Authors:  Emma E Wolters; Sandeep S V Golla; Tessa Timmers; Rik Ossenkoppele; Chris W J van der Weijden; Philip Scheltens; Lothar Schwarte; Robert C Schuit; Albert D Windhorst; Frederik Barkhof; Maqsood Yaqub; Adriaan A Lammertsma; Ronald Boellaard; Bart N M van Berckel
Journal:  EJNMMI Res       Date:  2018-08-15       Impact factor: 3.138

6.  First in human evaluation of [18F]PK-209, a PET ligand for the ion channel binding site of NMDA receptors.

Authors:  Jasper van der Aart; Sandeep S V Golla; Marieke van der Pluijm; Lothar A Schwarte; Robert C Schuit; Pieter J Klein; Athanasios Metaxas; Albert D Windhorst; Ronald Boellaard; Adriaan A Lammertsma; Bart N M van Berckel
Journal:  EJNMMI Res       Date:  2018-07-27       Impact factor: 3.138

7.  Reconstruction for time-domain in vivo EPR 3D multigradient oximetric imaging--a parallel processing perspective.

Authors:  Christopher D Dharmaraj; Kishan Thadikonda; Anthony R Fletcher; Phuc N Doan; Nallathamby Devasahayam; Shingo Matsumoto; Calvin A Johnson; John A Cook; James B Mitchell; Sankaran Subramanian; Murali C Krishna
Journal:  Int J Biomed Imaging       Date:  2009-08-05

8.  Quantification of the novel N-methyl-d-aspartate receptor ligand [11C]GMOM in man.

Authors:  Thalia F van der Doef; Sandeep S V Golla; Pieter J Klein; Gisela M Oropeza-Seguias; Robert C Schuit; Athanasios Metaxas; Ellen Jobse; Lothar A Schwarte; Albert D Windhorst; Adriaan A Lammertsma; Bart N M van Berckel; Ronald Boellaard
Journal:  J Cereb Blood Flow Metab       Date:  2015-10-05       Impact factor: 6.200

9.  Hippocampal [18F]flortaucipir BPND corrected for possible spill-in of the choroid plexus retains strong clinico-pathological relationships.

Authors:  Emma E Wolters; Rik Ossenkoppele; Sandeep Sv Golla; Sander Cj Verfaillie; Tessa Timmers; Denise Visser; Hayel Tuncel; Emma M Coomans; Albert D Windhorst; Philip Scheltens; Wiesje M van der Flier; Ronald Boellaard; Bart Nm van Berckel
Journal:  Neuroimage Clin       Date:  2019-12-02       Impact factor: 4.881

10.  Regional [18F]flortaucipir PET is more closely associated with disease severity than CSF p-tau in Alzheimer's disease.

Authors:  Emma E Wolters; Rik Ossenkoppele; Sander C J Verfaillie; Emma M Coomans; Tessa Timmers; Denise Visser; Hayel Tuncel; Sandeep S V Golla; Albert D Windhorst; Ronald Boellaard; Wiesje M van der Flier; Charlotte E Teunissen; Philip Scheltens; Bart N M van Berckel
Journal:  Eur J Nucl Med Mol Imaging       Date:  2020-04-14       Impact factor: 9.236

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