Literature DB >> 12200444

A complex of the Srb8, -9, -10, and -11 transcriptional regulatory proteins from yeast.

Tilman Borggrefe1, Ralph Davis, Hediye Erdjument-Bromage, Paul Tempst, Roger D Kornberg.   

Abstract

The Srb8, -9, -10, and -11 proteins of yeast have been isolated as a discrete, stoichiometric complex. The isolated complex phosphorylates the C-terminal domain (CTD) of the largest subunit of RNA polymerase II at serines 2 and 5. In addition to the previously reported human homologs of Srb10 and 11, we have identified TRAP230/ARC240 and TRAP240/ARC250 as the human homologs of Srb8 and Srb9, showing the entire Srb8/9/10/11 complex is conserved from yeast to humans.

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Year:  2002        PMID： 12200444     DOI： 10.1074/jbc.M207195200

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  81 in total

1.  Distinct role of Mediator tail module in regulation of SAGA-dependent, TATA-containing genes in yeast.

Authors:  Suraiya A Ansari; Mythily Ganapathi; Joris J Benschop; Frank C P Holstege; Joseph T Wade; Randall H Morse
Journal:  EMBO J       Date:  2011-10-04       Impact factor: 11.598

2.  A chromatin-remodeling protein is a component of fission yeast mediator.

Authors:  Olga Khorosjutina; Paulina H Wanrooij; Julian Walfridsson; Zsolt Szilagyi; Xuefeng Zhu; Vera Baraznenok; Karl Ekwall; Claes M Gustafsson
Journal:  J Biol Chem       Date:  2010-07-09       Impact factor: 5.157

3.  Antagonistic interactions between the cAMP-dependent protein kinase and Tor signaling pathways modulate cell growth in Saccharomyces cerevisiae.

Authors:  Vidhya Ramachandran; Paul K Herman
Journal:  Genetics       Date:  2010-11-15       Impact factor: 4.562

Review 4.  The mediator of RNA polymerase II.

Authors:  Erik Blazek; Gerhard Mittler; Michael Meisterernst
Journal:  Chromosoma       Date:  2005-02-03       Impact factor: 4.316

5.  Transcriptional activating regions target attached substrates to a cyclin-dependent kinase.

Authors:  Aseem Z Ansari; Anuja Ogirala; Mark Ptashne
Journal:  Proc Natl Acad Sci U S A       Date:  2005-02-01       Impact factor: 11.205

6.  Distinct roles for Mediator Cdk8 module subunits in Drosophila development.

Authors:  Nicolas Loncle; Muriel Boube; Laurent Joulia; Claire Boschiero; Michel Werner; David L Cribbs; Henri-Marc Bourbon
Journal:  EMBO J       Date:  2007-02-08       Impact factor: 11.598

7.  The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator.

Authors:  Matthew T Knuesel; Krista D Meyer; Aaron J Donner; Joaquin M Espinosa; Dylan J Taatjes
Journal:  Mol Cell Biol       Date:  2008-12-01       Impact factor: 4.272

8.  A genetic screen identifies novel polycomb group genes in Drosophila.

Authors:  Andrés Gaytán de Ayala Alonso; Luis Gutiérrez; Cornelia Fritsch; Bernadett Papp; Dirk Beuchle; Jürg Müller
Journal:  Genetics       Date:  2007-08       Impact factor: 4.562

9.  TRAP230/ARC240 and TRAP240/ARC250 Mediator subunits are functionally conserved through evolution.

Authors:  Camilla O Samuelsen; Vera Baraznenok; Olga Khorosjutina; Henrik Spahr; Thomas Kieselbach; Steen Holmberg; Claes M Gustafsson
Journal:  Proc Natl Acad Sci U S A       Date:  2003-05-08       Impact factor: 11.205

10.  Promoter-dependent roles for the Srb10 cyclin-dependent kinase and the Hda1 deacetylase in Tup1-mediated repression in Saccharomyces cerevisiae.

Authors:  Sarah R Green; Alexander D Johnson
Journal:  Mol Biol Cell       Date:  2004-07-07       Impact factor: 4.138
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