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Literature DB >> 12200034

Animal models of oxidative stress, aging, and therapeutic antioxidant interventions.

Abstract

Oxidative stress is a ubiquitous phenomena in all cell types, and it is primarily produced in mitochondria which are essential for multicellular life. Oxidative stress targets can be wide ranging and include nucleic acids and a variety of macromolecules. This review discusses the role of oxidative stress in the context of animal models, focusing in particular on animal models of aging, as well as the development of a new class of therapeutic small molecular weight antioxidants that have proven effective in extending the lifespan of a simple invertebrate nematode.

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Year: 2002 PMID： 12200034 DOI： 10.1016/s1357-2725(02)00086-9

Source DB: PubMed Journal: Int J Biochem Cell Biol ISSN： 1357-2725 Impact factor: 5.085

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Cited

20 in total

1. Involvement of the up-regulated FoxO1 expression in follicular granulosa cell apoptosis induced by oxidative stress.

Authors: Ming Shen; Fei Lin; Jiaqing Zhang; Yiting Tang; Wei-Kang Chen; Honglin Liu
Journal: J Biol Chem Date: 2012-06-04 Impact factor: 5.157

2. Conserved selenoprotein synthesis is not critical for oxidative stress defence and the lifespan of Drosophila.

Authors: Mitsuko Hirosawa-Takamori; Ho-Ryun Chung; Herbert Jäckle
Journal: EMBO Rep Date: 2004-02-20 Impact factor: 8.807

3. Measuring "free" iron levels in Caenorhabditis elegans using low-temperature Fe(III) electron paramagnetic resonance spectroscopy.

Authors: Kira T Pate; Natalie A Rangel; Brian Fraser; Matthew H S Clement; Chandra Srinivasan
Journal: Anal Biochem Date: 2006-09-12 Impact factor: 3.365

4. Age-dependent changes in glutathione-s-transferase: correlation with total plasma antioxidant potential and red cell intracellular glutathione.

Authors: Pawan Kumar Maurya; Syed Ibrahim Rizvi
Journal: Indian J Clin Biochem Date: 2010-09-14

5. Protective Effects of Crocus Sativus L. Extract and Crocin against Chronic-Stress Induced Oxidative Damage of Brain, Liver and Kidneys in Rats.

Authors: Ahmad Reza Bandegi; Ali Rashidy-Pour; Abbas Ali Vafaei; Behshid Ghadrdoost
Journal: Adv Pharm Bull Date: 2014-12-31

10. Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.

Authors: Douglas B Kell
Journal: BMC Med Genomics Date: 2009-01-08 Impact factor: 3.063

Animal models of oxidative stress, aging, and therapeutic antioxidant interventions.

1. Involvement of the up-regulated FoxO1 expression in follicular granulosa cell apoptosis induced by oxidative stress.

2. Conserved selenoprotein synthesis is not critical for oxidative stress defence and the lifespan of Drosophila.

3. Measuring "free" iron levels in Caenorhabditis elegans using low-temperature Fe(III) electron paramagnetic resonance spectroscopy.

4. Age-dependent changes in glutathione-s-transferase: correlation with total plasma antioxidant potential and red cell intracellular glutathione.

5. Protective Effects of Crocus Sativus L. Extract and Crocin against Chronic-Stress Induced Oxidative Damage of Brain, Liver and Kidneys in Rats.

Review 6. Markers of oxidative stress in erythrocytes and plasma during aging in humans.

7. Alterations in antioxidant enzymes during aging in humans.

8. Compounds that confer thermal stress resistance and extended lifespan.

9. Plasma antioxidants and human aging: a study on healthy elderly Tunisian population.

10. Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases.