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Literature DB >> 12198717

APC as a checkpoint gene: the beginning or the end?

Vincent W Yang.

Abstract

Entities: Disease

Mesh：

Year: 2002 PMID： 12198717 PMCID： PMC2703726 DOI： 10.1053/gast.2002.35773

Source DB: PubMed Journal: Gastroenterology ISSN： 0016-5085 Impact factor: 22.682

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32 in total

Review 1. Dishevelled: at the crossroads of divergent intracellular signaling pathways.

Authors: M Boutros; M Mlodzik
Journal: Mech Dev Date: 1999-05 Impact factor: 1.882

Review 2. The many faces of the tumor suppressor gene APC.

Authors: J H van Es; R H Giles; H C Clevers
Journal: Exp Cell Res Date: 2001-03-10 Impact factor: 3.905

3. Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover.

Authors: B R Henderson
Journal: Nat Cell Biol Date: 2000-09 Impact factor: 28.824

Review 4. Colon cancer screening.

Authors: R W Burt
Journal: Gastroenterology Date: 2000-09 Impact factor: 22.682

5. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1.

Authors: S Satoh; Y Daigo; Y Furukawa; T Kato; N Miwa; T Nishiwaki; T Kawasoe; H Ishiguro; M Fujita; T Tokino; Y Sasaki; S Imaoka; M Murata; T Shimano; Y Yamaoka; Y Nakamura
Journal: Nat Genet Date: 2000-03 Impact factor: 38.330

6. Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.

Authors: Barbara Lustig; Boris Jerchow; Martin Sachs; Sigrid Weiler; Torsten Pietsch; Uwe Karsten; Marc van de Wetering; Hans Clevers; Peter M Schlag; Walter Birchmeier; Jürgen Behrens
Journal: Mol Cell Biol Date: 2002-02 Impact factor: 4.272

7. Asef, a link between the tumor suppressor APC and G-protein signaling.

Authors: Y Kawasaki; T Senda; T Ishidate; R Koyama; T Morishita; Y Iwayama; O Higuchi; T Akiyama
Journal: Science Date: 2000-08-18 Impact factor: 47.728

8. Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm.

Authors: K L Neufeld; D A Nix; H Bogerd; Y Kang; M C Beckerle; B R Cullen; R L White
Journal: Proc Natl Acad Sci U S A Date: 2000-10-24 Impact factor: 11.205

APC as a checkpoint gene: the beginning or the end?

Review 1. Dishevelled: at the crossroads of divergent intracellular signaling pathways.

Review 2. The many faces of the tumor suppressor gene APC.

3. Nuclear-cytoplasmic shuttling of APC regulates beta-catenin subcellular localization and turnover.

Review 4. Colon cancer screening.

5. AXIN1 mutations in hepatocellular carcinomas, and growth suppression in cancer cells by virus-mediated transfer of AXIN1.

6. Negative feedback loop of Wnt signaling through upregulation of conductin/axin2 in colorectal and liver tumors.

7. Asef, a link between the tumor suppressor APC and G-protein signaling.

8. Adenomatous polyposis coli protein contains two nuclear export signals and shuttles between the nucleus and cytoplasm.

9. Mutations in the APC tumour suppressor gene cause chromosomal instability.

10. A role for the Adenomatous Polyposis Coli protein in chromosome segregation.

1. Chemoprevention of familial adenomatous polyposis by bromo-noscapine (EM011) in the Apc(Min/+) mouse model.

2. Molecular Genetics of Colorectal Cancer: An Overview.

3. Clusterin as a biomarker in murine and human intestinal neoplasia.

Review 4. The regulation of β-catenin activity and function in cancer: therapeutic opportunities.