Literature DB >> 12198400

Executive dysfunction and clinical outcome in chronic alcoholics.

Yasushi Moriyama1, Masaru Mimura, Motoichiro Kato, Aihide Yoshino, Tsunekatsu Hara, Haruo Kashima, Akinobu Kato, Akiharu Watanabe.   

Abstract

BACKGROUND: The purpose of this study was to investigate which of 12 neuropsychological tests predict alcoholic patients' alcohol-specific and/or alcoholic-nonspecific outcome. Our hypothesis was that the ecologically valid neuropsychological tests that measure executive function are better predictors of alcoholics' functional outcome.
METHODS: We administered 12 neuropsychological tests to chronic alcoholics. Included in the tests were tasks of Reaction Time, Symbol Digit Modalities, Figure Position, Digit Span, Block Design, Trail Making, and six subtests of a battery called the Behavioral Assessment of the Dysexecutive Syndrome (BADS). Previous investigators have suggested that the BADS has ecological validity. Twenty-two male alcoholics were compared with 15 nonalcoholic control subjects on these neuropsychological measures 7 weeks after detoxification. Two functional outcome indices, i.e., resumption of drinking and occupation, were evaluated 18 months after discharge.
RESULTS: The total profile score and the score on three of the six subtests of the BADS were lower in alcoholics than in nonalcoholic controls. Alcoholics' performance on the BADS predicted alcohol-nonspecific outcome (occupation) but not alcohol-specific (drinking) outcome. In contrast, other neuropsychological tests did not predict either of the two outcome indices.
CONCLUSIONS: The BADS total profile score is related to alcohol-nonspecific outcome but not to alcohol-specific outcome.

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Mesh:

Year:  2002        PMID: 12198400     DOI: 10.1097/01.ALC.0000026103.08053.86

Source DB:  PubMed          Journal:  Alcohol Clin Exp Res        ISSN: 0145-6008            Impact factor:   3.455


  11 in total

Review 1.  Executive Functioning in Alcohol Use Studies: A Brief Review of Findings and Challenges in Assessment.

Authors:  Anne M Day; Christopher W Kahler; David C Ahern; Uraina S Clark
Journal:  Curr Drug Abuse Rev       Date:  2015

Review 2.  Executive Functions, Memory, and Social Cognitive Deficits and Recovery in Chronic Alcoholism: A Critical Review to Inform Future Research.

Authors:  Anne-Pascale Le Berre; Rosemary Fama; Edith V Sullivan
Journal:  Alcohol Clin Exp Res       Date:  2017-07-04       Impact factor: 3.455

3.  Testing the nanoparticle-allostatic cross-adaptation-sensitization model for homeopathic remedy effects.

Authors:  Iris R Bell; Mary Koithan; Audrey J Brooks
Journal:  Homeopathy       Date:  2013-01       Impact factor: 1.444

4.  Chronic alcohol consumption and its effect on nodes of frontocerebellar and limbic circuitry: comparison of effects in France and the United States.

Authors:  Anne-Pascale Le Berre; Anne-Lise Pitel; Sandra Chanraud; Hélène Beaunieux; Francis Eustache; Jean-Luc Martinot; Michel Reynaud; Catherine Martelli; Torsten Rohlfing; Edith V Sullivan; Adolf Pfefferbaum
Journal:  Hum Brain Mapp       Date:  2014-03-17       Impact factor: 5.038

5.  Up-Regulation of PKR Signaling Pathway by Ethanol Displays an Age of Onset-Dependent Relationship.

Authors:  Jeremy W Duncan; Shakevia Johnson; Xiao Zhang; Baoying Zheng; Jia Luo; Xiao-Ming Ou; Craig A Stockmeier; Jun Ming Wang
Journal:  Alcohol Clin Exp Res       Date:  2016-09-20       Impact factor: 3.455

Review 6.  Cognitive training for impaired neural systems in neuropsychiatric illness.

Authors:  Sophia Vinogradov; Melissa Fisher; Etienne de Villers-Sidani
Journal:  Neuropsychopharmacology       Date:  2011-11-02       Impact factor: 7.853

7.  Effect of methamphetamine dependence on everyday functional ability.

Authors:  Brook L Henry; Arpi Minassian; William Perry
Journal:  Addict Behav       Date:  2010-02-01       Impact factor: 3.913

Review 8.  A Patient-Tailored Evidence-Based Approach for Developing Early Neuropsychological Training Programs in Addiction Settings.

Authors:  Benjamin Rolland; Fabien D'Hondt; Solène Montègue; Mélanie Brion; Eric Peyron; Julia D'Aviau de Ternay; Philippe de Timary; Mikaïl Nourredine; Pierre Maurage
Journal:  Neuropsychol Rev       Date:  2019-01-03       Impact factor: 7.444

Review 9.  [Alcohol induced cognitive deficits].

Authors:  Elisabeth Weiss; Evelin M Singewald; Beatrix Ruepp; Josef Marksteiner
Journal:  Wien Med Wochenschr       Date:  2013-07-19

10.  Frontal brain dysfunction in alcoholism with and without antisocial personality disorder.

Authors:  Marlene Oscar-Berman; Mary M Valmas; Kayle S Sawyer; Shalene M Kirkley; David A Gansler; Diane Merritt; Ashley Couture
Journal:  Neuropsychiatr Dis Treat       Date:  2009-06-10       Impact factor: 2.570

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