BACKGROUND: Analysing a 12-lead surface electrocardiogram (ECG), the inter-lead variability of the P wave interval, i.e. P wave dispersion, is defined as the difference between the maximum and the minimum P wave duration. Our aim was to assess the effect of haemodialysis on P wave duration and dispersion in non-diabetic patients with end-stage renal failure on chronic haemodialysis. METHODS: Twenty-eight patients (14 men and 14 women, mean age 58+/-16 years, average duration of dialysis 4.5+/-2.8 years) were examined. Prior to haemodialysis, echocardiography (M-mode and two-dimensional) was performed. Haemodialysis sessions were carried out with polysulfone dialysers and bicarbonate dialysate fluids. Twelve-lead ECGs were recorded at the beginning, 15 and 30 min after starting dialysis, at the end, and 2 h after completion of each session. Ionic parameters were checked during the study. P wave durations were measured with calipers in three consecutive complexes of each lead by one observer. RESULTS: P maximum was 58+/-16 ms at the beginning, and showed an increase by the end of dialysis to 98+/-8.9 ms (P<0.0001). Pre-dialysis P dispersion was 23+/-10 ms and increased to 41+/-16 ms by the end of the sessions (P<0.0001). In patients with a left atrial diameter larger than 45 mm, P dispersion increased from 23+/-11 to 53+/-10 ms (P<0.0003) by the end of the sessions. CONCLUSIONS: According to our results, ionic imbalance and dialysis itself may cause changes in P duration and dispersion simultaneously.
BACKGROUND: Analysing a 12-lead surface electrocardiogram (ECG), the inter-lead variability of the P wave interval, i.e. P wave dispersion, is defined as the difference between the maximum and the minimum P wave duration. Our aim was to assess the effect of haemodialysis on P wave duration and dispersion in non-diabeticpatients with end-stage renal failure on chronic haemodialysis. METHODS: Twenty-eight patients (14 men and 14 women, mean age 58+/-16 years, average duration of dialysis 4.5+/-2.8 years) were examined. Prior to haemodialysis, echocardiography (M-mode and two-dimensional) was performed. Haemodialysis sessions were carried out with polysulfone dialysers and bicarbonate dialysate fluids. Twelve-lead ECGs were recorded at the beginning, 15 and 30 min after starting dialysis, at the end, and 2 h after completion of each session. Ionic parameters were checked during the study. P wave durations were measured with calipers in three consecutive complexes of each lead by one observer. RESULTS: P maximum was 58+/-16 ms at the beginning, and showed an increase by the end of dialysis to 98+/-8.9 ms (P<0.0001). Pre-dialysis P dispersion was 23+/-10 ms and increased to 41+/-16 ms by the end of the sessions (P<0.0001). In patients with a left atrial diameter larger than 45 mm, P dispersion increased from 23+/-11 to 53+/-10 ms (P<0.0003) by the end of the sessions. CONCLUSIONS: According to our results, ionic imbalance and dialysis itself may cause changes in P duration and dispersion simultaneously.
Authors: Hande Ozportakal; Abdullah Ozkok; Ozlem Alkan; Ahmet Sait Bulut; Memduha Boyraz; Mehmet Inanir; Goksel Acar; Ali Riza Odabas Journal: Int Urol Nephrol Date: 2016-12-10 Impact factor: 2.370
Authors: Alida Páll; Árpád Czifra; Veronika Sebestyén; Gergely Becs; Csaba Kun; József Balla; György Paragh; István Lőrincz; Dénes Páll; Tamás János Padra; Anupam Agarwal; Abolfazl Zarjou; Zoltán Szabó Journal: Int Urol Nephrol Date: 2015-11-11 Impact factor: 2.370
Authors: David M Charytan; Robert Foley; Peter A McCullough; John D Rogers; Peter Zimetbaum; Charles A Herzog; James A Tumlin Journal: Clin J Am Soc Nephrol Date: 2016-01-13 Impact factor: 8.237