BACKGROUND: There are not enough large epidemiological population-based studies of biopsy-proven nephropathies with detailed clinical and histopathological data. METHODS: The Glomerulonephritis Registry of the Spanish Society of Nephrology has obtained data from 7016 patients with biopsied renal diseases between 1994 and 1999, investigating prevalence, incidence and clinical and histopathological data. Biopsies of transplant kidneys have not been considered. RESULTS: The observed biopsy rate for all ages is 4.8 per 100 000 inhabitants. A male predominance is seen for all age groups. The most common clinical syndrome at any age is nephrotic syndrome. The prevalence of hypertension is higher in adults and elderly patients. The most common pathologies are IgA nephropathy, focal glomerulosclerosis, membranous nephropathy and lupus nephritis. The mean annual incidence (per million of population) of the most common nephropathies is IgA nephropathy 7.9, focal segmental glomerulosclerosis 6.4, membranous nephropathy 6.2, lupus nephritis 5.6, minimal-change disease 4.8, nephroangiosclerosis 4.6, vasculitis 4.3, membranoproliferative glomerulonephritis 3.6 and amyloidosis 3.3. In children, the most frequent causes are minimal-change disease, IgA nephropathy and focal glomerulosclerosis. In adults, the most common diagnoses are IgA nephropathy, lupus nephritis, and focal glomerulosclerosis. In elderly patients, the most frequently reported pathologies are vasculitis, membranous nephropathy and amyloidosis. Membranous nephropathy has increased in incidence in recent years. CONCLUSIONS: We provide representative population-based descriptive data on native biopsy-proven renal diseases in Spain.
BACKGROUND: There are not enough large epidemiological population-based studies of biopsy-proven nephropathies with detailed clinical and histopathological data. METHODS: The Glomerulonephritis Registry of the Spanish Society of Nephrology has obtained data from 7016 patients with biopsied renal diseases between 1994 and 1999, investigating prevalence, incidence and clinical and histopathological data. Biopsies of transplant kidneys have not been considered. RESULTS: The observed biopsy rate for all ages is 4.8 per 100 000 inhabitants. A male predominance is seen for all age groups. The most common clinical syndrome at any age is nephrotic syndrome. The prevalence of hypertension is higher in adults and elderly patients. The most common pathologies are IgA nephropathy, focal glomerulosclerosis, membranous nephropathy and lupus nephritis. The mean annual incidence (per million of population) of the most common nephropathies is IgA nephropathy 7.9, focal segmental glomerulosclerosis 6.4, membranous nephropathy 6.2, lupus nephritis 5.6, minimal-change disease 4.8, nephroangiosclerosis 4.6, vasculitis 4.3, membranoproliferative glomerulonephritis 3.6 and amyloidosis 3.3. In children, the most frequent causes are minimal-change disease, IgA nephropathy and focal glomerulosclerosis. In adults, the most common diagnoses are IgA nephropathy, lupus nephritis, and focal glomerulosclerosis. In elderly patients, the most frequently reported pathologies are vasculitis, membranous nephropathy and amyloidosis. Membranous nephropathy has increased in incidence in recent years. CONCLUSIONS: We provide representative population-based descriptive data on native biopsy-proven renal diseases in Spain.
Authors: Asheeta Gupta; Joanna Campion-Smith; Wesley Hayes; Jane E Deal; Rodney D Gilbert; Carole Inward; Brian A Judd; Rajesh G Krishnan; Stephen D Marks; Catherine O'Brien; Mohan Shenoy; Manish D Sinha; Yincent Tse; Kay Tyerman; Meeta Mallik; Farida Hussain Journal: Pediatr Nephrol Date: 2015-11-02 Impact factor: 3.714
Authors: Savas Ozturk; Abdullah Sumnu; Nurhan Seyahi; Mustafa Gullulu; Murat Sipahioglu; Serra Artan; Zerrin Bicik; Sim Kutlay; Mustafa Keles; Deren Oygar; Ali Riza Odabas; Mansur Kayatas; Belda Dursun; Hayriye Sayarlioglu; Sinan Trablus; Dilek Guven Taymez; Ali Abbas Ozdemir; Gulizar Manga Sahin; Bulent Altun; Alper Azak; Lutfullah Altintepe; Gultekin Suleymanlar; Mehmet Koc; Yilmaz Selcuk; Rumeyza Kazancioglu; Reha Erkoc; Meltem Gursu; Mehmet Kucuk; Selma Alagoz Akcaoglu; Abdulmecid Yıldız; Aydin Unal; Ozger Akarsu; Kenan Ates; Erdem Cankaya; Aydin Turkmen Journal: Int Urol Nephrol Date: 2014-09-30 Impact factor: 2.370
Authors: Dita Maixnerova; Eva Jancova; Jelena Skibova; Romana Rysava; Ivan Rychlik; Ondrej Viklicky; Miroslav Merta; Alexander Kolsky; Jana Reiterova; Michaela Neprasova; Jana Kidorova; Eva Honsova; Vladimir Tesar Journal: J Nephrol Date: 2014-04-23 Impact factor: 3.902