Literature DB >> 12198046

Issues in the design and interpretation of minimum alveolar anesthetic concentration (MAC) studies.

James M Sonner1.   

Abstract

IMPLICATIONS: The two experimental designs (quantal and bracketing) used for population minimum alveolar anesthetic concentration studies give equivalent results. An expression relating variability in terms of Hill coefficients and SD is presented. Evolutionary implications of low population variability in anesthetic phenotypes is discussed.

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Year:  2002        PMID： 12198046     DOI： 10.1097/00000539-200209000-00021

Source DB:  PubMed          Journal:  Anesth Analg        ISSN： 0003-2999            Impact factor:   5.108


  18 in total

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Review 2.  Acute alcohol action and desensitization of ligand-gated ion channels.

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4.  Anesthetic sensitivity: learning to fly.

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5.  Isoflurane potency in mice from the first and second parity.

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6.  Tolerance to isoflurane does not occur in developing Xenopus laevis tadpoles.

Authors:  Pavle S Milutinovic; Jing Zhao; James M Sonner
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7.  Effects of Standard and Sustained-release Buprenorphine on the Minimum Alveolar Concentration of Isoflurane in C57BL/6 Mice.

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8.  Genetic effects in Drosophila on the potency of diverse general anesthetics: a distinctive pattern of altered sensitivity.

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9.  The Mouse as a Model Organism for Assessing Anesthetic Sensitivity.

Authors:  Andrzej Z Wasilczuk; Kaitlyn L Maier; Max B Kelz
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Review 10.  A hypothesis on the origin and evolution of the response to inhaled anesthetics.

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Journal:  Anesth Analg       Date:  2008-09       Impact factor: 5.108
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