OBJECTIVE: To assess whether general risk factors for depression are also markers of depression in patients with Parkinson's disease (PD) and to identify additional disease-specific markers. METHOD: A two-step logistic regression was performed on data from 161 consecutively referred PD patients, 40 of whom suffered from major depressive disorder. A first logistic model was created with five general risk factors for depression. Next, five potential disease-specific markers were added to see whether this would improve the model. RESULTS: The logistic model of general risk factors for depression also predicted depression in PD patients. A family history of depression was the most important marker. 'Right-sided onset' was the only disease-specific marker that improved the model. CONCLUSION: Established risk factors for depression in the general population are also markers of depression in PD. The importance of correcting for general risk factors for depression in the search for disease-specific risk factors is stressed. Copyright Blackwell Munksgaard 2002.
OBJECTIVE: To assess whether general risk factors for depression are also markers of depression in patients with Parkinson's disease (PD) and to identify additional disease-specific markers. METHOD: A two-step logistic regression was performed on data from 161 consecutively referred PDpatients, 40 of whom suffered from major depressive disorder. A first logistic model was created with five general risk factors for depression. Next, five potential disease-specific markers were added to see whether this would improve the model. RESULTS: The logistic model of general risk factors for depression also predicted depression in PDpatients. A family history of depression was the most important marker. 'Right-sided onset' was the only disease-specific marker that improved the model. CONCLUSION: Established risk factors for depression in the general population are also markers of depression in PD. The importance of correcting for general risk factors for depression in the search for disease-specific risk factors is stressed. Copyright Blackwell Munksgaard 2002.
Authors: Daniel Weintraub; Knashawn H Morales; John E Duda; Paul J Moberg; Matthew B Stern Journal: Parkinsonism Relat Disord Date: 2006-06-22 Impact factor: 4.891
Authors: Leonardo Almeida; Bilal Ahmed; Roger Walz; Sol De Jesus; Addie Patterson; Daniel Martinez-Ramirez; David Vaillancourt; Dawn Bowers; Herbert Ward; Michael S Okun; Nikolaus R McFarland Journal: Mov Disord Clin Pract Date: 2016-06-24
Authors: A Srivastava; M-X Tang; H Mejia-Santana; L Rosado; E D Louis; E Caccappolo; C Comella; A Colcher; A Siderowf; D Jennings; M Nance; S Bressman; W K Scott; C Tanner; S Mickel; H Andrews; C Waters; S Fahn; L Cote; S Frucht; B Ford; R N Alcalay; B Ross; M Orbe Reilly; M Rezak; K Novak; J H Friedman; R D Pfeiffer; L Marsh; B Hiner; D Merle; R Ottman; L N Clark; K Marder Journal: Parkinsonism Relat Disord Date: 2011-12 Impact factor: 4.891
Authors: Richard B Dewey; Aanchal Taneja; Shawn M McClintock; C Munro Cullum; Richard B Dewey; Ira Bernstein; Mustafa M Husain Journal: Cogn Behav Neurol Date: 2012-09 Impact factor: 1.600