Literature DB >> 12196989

A liquid-phase peptide synthesis in cyclohexane-based biphasic thermomorphic systems.

Kazuhiro Chiba1, Yusuke Kono, Shokaku Kim, Kohsuke Nishimoto, Yoshikazu Kitano, Masahiro Tada.   

Abstract

Combinations of typical organic solvents composed of cyclohexane and qualified aprotic polar organic solvents were found to realize an effective, biphasic thermomorphic system in arbitrary ratios of upper and lower phases that enable a practical application of a liquid-phase peptide synthesis.

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Year:  2002        PMID: 12196989     DOI: 10.1039/b205156g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  2 in total

1.  AJIPHASE®: A Highly Efficient Synthetic Method for One-Pot Peptide Elongation in the Solution Phase by an Fmoc Strategy.

Authors:  Daisuke Takahashi; Tatsuji Inomata; Tatsuya Fukui
Journal:  Angew Chem Int Ed Engl       Date:  2017-06-07       Impact factor: 15.336

2.  Silylated Tag-Assisted Peptide Synthesis: Continuous One-Pot Elongation for the Production of Difficult Peptides under Environmentally Friendly Conditions.

Authors:  Shinya Yano; Toshihiro Mori; Hideki Kubota
Journal:  Molecules       Date:  2021-06-08       Impact factor: 4.411

  2 in total

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