Literature DB >> 12196954

Membrane disruption ability of facially amphiphilic helical peptides.

Yvonne R Vandenburg1, Bradley D Smith, Eric Biron, Normand Voyer.   

Abstract

A helical 14-residue peptide containing four polar, but uncharged, benzo-21-crown-7 side-chains aligned along one face induces significantly more vesicle leakage than analogous 21-mer or 7-mer peptides.

Mesh：

Substances：

Year:  2002        PMID： 12196954     DOI： 10.1039/b204640g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  6 in total

1.  Structure-activity relationships, kinetics, selectivity, and mechanistic studies of synthetic hydraphile channels in bacterial and mammalian cells.

Authors:  W Matthew Leevy; Seth T Gammon; Tatiana Levchenko; David D Daranciang; Oscar Murillo; Vladimir Torchilin; David Piwnica-Worms; James E Huettner; George W Gokel
Journal:  Org Biomol Chem       Date:  2005-08-26       Impact factor: 3.876

2.  Insights on the interactions of synthetic amphipathic peptides with model membranes as revealed by 31P and 2H solid-state NMR and infrared spectroscopies.

Authors:  Marise Ouellet; Geneviève Bernard; Normand Voyer; Michèle Auger
Journal:  Biophys J       Date:  2006-03-13       Impact factor: 4.033

3.  Membrane interactions of synthetic peptides with antimicrobial potential: effect of electrostatic interactions and amphiphilicity.

Authors:  Matthieu Fillion; Geneviève Valois-Paillard; Aurélien Lorin; Mathieu Noël; Normand Voyer; Michèle Auger
Journal:  Probiotics Antimicrob Proteins       Date:  2015-03       Impact factor: 4.609

4.  Determining the mode of action involved in the antimicrobial activity of synthetic peptides: a solid-state NMR and FTIR study.

Authors:  Aurélien Lorin; Mathieu Noël; Marie-Ève Provencher; Vanessa Turcotte; Sébastien Cardinal; Patrick Lagüe; Normand Voyer; Michèle Auger
Journal:  Biophys J       Date:  2012-10-02       Impact factor: 4.033

5.  Protein Structure Insights into the Bilayer Interactions of the Saposin-Like Domain of Solanum tuberosum Aspartic Protease.

Authors:  Brian C Bryksa; Rickey Y Yada
Journal:  Sci Rep       Date:  2017-12-05       Impact factor: 4.379

Review 6.  Membrane Active Antimicrobial Peptides: Translating Mechanistic Insights to Design.

Authors:  Jianguo Li; Jun-Jie Koh; Shouping Liu; Rajamani Lakshminarayanan; Chandra S Verma; Roger W Beuerman
Journal:  Front Neurosci       Date:  2017-02-14       Impact factor: 4.677
  6 in total

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