Literature DB >> 12196669

Increased CSF hypocretin-1 (orexin-A) in restless legs syndrome.

R P Allen1, E Mignot, B Ripley, S Nishino, C J Earley.   

Abstract

Hypocretin-1 levels were increased in evening CSF samples from subjects with restless legs syndrome, indicating altered hypocretin transmission in this sleep disorder. Increases in CSF hypocretin-1 levels were most striking in patients with early-onset restless legs syndrome.

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Year:  2002        PMID： 12196669     DOI： 10.1212/wnl.59.4.639

Source DB:  PubMed          Journal:  Neurology        ISSN： 0028-3878            Impact factor:   9.910


  11 in total

1.  [The neurotransmitter, hypocretin. An overview].

Authors:  C Baumann; C Bassetti
Journal:  Nervenarzt       Date:  2004-04       Impact factor: 1.214

2.  Heart rate changes accompanying periodic leg movements during sleep in narcoleptic patients.

Authors:  Raffaele Ferri; Marco Zucconi; David B Rye
Journal:  Sleep       Date:  2011-04-01       Impact factor: 5.849

3.  Ectopic overexpression of orexin alters sleep/wakefulness states and muscle tone regulation during REM sleep in mice.

Authors:  Jon T Willie; Hitomi Takahira; Megumi Shibahara; Junko Hara; Mika Nomiyama; Masashi Yanagisawa; Takeshi Sakurai
Journal:  J Mol Neurosci       Date:  2010-08-14       Impact factor: 3.444

4.  CSF hypocretin-1 levels in narcolepsy, Kleine-Levin syndrome, and other hypersomnias and neurological conditions.

Authors:  Y Dauvilliers; C R Baumann; B Carlander; M Bischof; T Blatter; M Lecendreux; F Maly; A Besset; J Touchon; M Billiard; M Tafti; C L Bassetti
Journal:  J Neurol Neurosurg Psychiatry       Date:  2003-12       Impact factor: 10.154

5.  Hypothalamic orexin's role in exacerbated cutaneous vasodilation responses to an anxiogenic stimulus in a surgical menopause model.

Authors:  Lauren M Federici; Izabela Facco Caliman; Andrei I Molosh; Stephanie D Fitz; William A Truitt; Pascal Bonaventure; Janet S Carpenter; Anantha Shekhar; Philip L Johnson
Journal:  Psychoneuroendocrinology       Date:  2015-12-18       Impact factor: 4.905

Review 6.  Hypocretin (orexin): role in normal behavior and neuropathology.

Authors:  Jerome M Siegel
Journal:  Annu Rev Psychol       Date:  2004       Impact factor: 24.137

7.  The seasonal pattern of restless legs syndrome in a sample from the Korean Health Insurance Review and Assessment Service national database.

Authors:  Seong Min Oh; Kyung-Lak Son; Seok-Jin Choi; Mi Hyun Lee; So Young Yoon; Yu Jin Lee
Journal:  J Clin Sleep Med       Date:  2021-05-01       Impact factor: 4.062

8.  Diagnosis and treatment of sleep disorders: a brief review for clinicians.

Authors:  Vivien C Abad; Christian Guilleminault
Journal:  Dialogues Clin Neurosci       Date:  2003-12       Impact factor: 5.986

Review 9.  New Insights into the Neurobiology of Restless Legs Syndrome.

Authors:  Sergi Ferré; Diego García-Borreguero; Richard P Allen; Christopher J Earley
Journal:  Neuroscientist       Date:  2018-07-26       Impact factor: 7.235

Review 10.  Understanding how discrete populations of hypothalamic neurons orchestrate complicated behavioral states.

Authors:  Allison K Graebner; Manasi Iyer; Matthew E Carter
Journal:  Front Syst Neurosci       Date:  2015-08-04
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