| Literature DB >> 12196108 |
E W Hillhouse1, H Randeva, G Ladds, D Grammatopoulos.
Abstract
Corticotropin-releasing hormone (CRH) and related peptides (urocortins, sauvagine, urotensin) play a central role in the co-ordination of autonomic, behavioural, cardiovascular, immune and endocrine responses to stressful stimuli. Their actions are mediated through activation of two types of G-protein-coupled receptors encoded by separate genes. In this review we focus on the diverse structural and functional characteristics of the family of CRH-like peptides and their receptors.Entities:
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Year: 2002 PMID: 12196108 DOI: 10.1042/bst0300428
Source DB: PubMed Journal: Biochem Soc Trans ISSN: 0300-5127 Impact factor: 5.407