Literature DB >> 12192157

First total synthesis of a novel monoterpenoid isoquinoline alkaloid, (+/-)-alangine.

Hiromitsu Takayama1, Maki Arai, Mariko Kitajima, Norio Aimi.   

Abstract

The structure including the stereochemistry of a novel monoterpenoid isoquinoline alkaloid, alangine, was confirmed by total synthesis via N-acyliminium cyclization to construct the isoquinoline skeleton and reductive cleavage of vinyl epoxide with Pd(0) catalyst.

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Year:  2002        PMID: 12192157     DOI: 10.1248/cpb.50.1141

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN: 0009-2363            Impact factor:   1.645


  1 in total

1.  Total synthesis of the alpha-glucosidase inhibitors schulzeine A, B, and C and a structural revision of schulzeine A.

Authors:  Edward G Bowen; Duncan J Wardrop
Journal:  J Am Chem Soc       Date:  2009-05-06       Impact factor: 15.419

  1 in total

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