Literature DB >> 12191465

All signaling is local?

Joseph Schlessinger1.   

Abstract

The mechanism of signal transmission following ligand stimulation of receptor tyrosine kinases in living cells is poorly understood. Recent studies have visualized the spatio-temporal pattern of EGF signaling, indicating that receptor density is an important factor in the mechanism of lateral propagation of local EGF signaling.

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Year:  2002        PMID： 12191465     DOI： 10.1016/s1097-2765(02)00607-x

Source DB:  PubMed          Journal:  Mol Cell        ISSN： 1097-2765            Impact factor:   17.970


  7 in total

1.  Growth factor pleiotropy is controlled by a receptor Tyr/Ser motif that acts as a binary switch.

Authors:  Mark A Guthridge; Jason A Powell; Emma F Barry; Frank C Stomski; Barbara J McClure; Hayley Ramshaw; Fernando A Felquer; Mara Dottore; Daniel T Thomas; Bik To; C Glenn Begley; Angel F Lopez
Journal:  EMBO J       Date:  2006-01-26       Impact factor: 11.598

Review 2.  Basic principles and emerging concepts in the redox control of transcription factors.

Authors:  Regina Brigelius-Flohé; Leopold Flohé
Journal:  Antioxid Redox Signal       Date:  2011-04-05       Impact factor: 8.401

Review 3.  Cell signaling by receptor tyrosine kinases.

Authors:  Mark A Lemmon; Joseph Schlessinger
Journal:  Cell       Date:  2010-06-25       Impact factor: 41.582

4.  Distinct domains in the SHP-2 phosphatase differentially regulate epidermal growth factor receptor/NF-kappaB activation through Gab1 in glioblastoma cells.

Authors:  Gurpreet S Kapoor; Yi Zhan; Gibbes R Johnson; Donald M O'Rourke
Journal:  Mol Cell Biol       Date:  2004-01       Impact factor: 4.272

5.  Frequency of HER2/neu overexpression in adenocarcinoma of the gastrointestinal system.

Authors:  Sadaf Farzand; Tahir Siddique; Kanwal Saba; Mulazim Hussain Bukhari
Journal:  World J Gastroenterol       Date:  2014-05-21       Impact factor: 5.742

6.  Bipartite inhibition of Drosophila epidermal growth factor receptor by the extracellular and transmembrane domains of Kekkon1.

Authors:  Diego Alvarado; Amy H Rice; Joseph B Duffy
Journal:  Genetics       Date:  2004-05       Impact factor: 4.562

7.  Heterogeneous intracellular trafficking dynamics of brain-derived neurotrophic factor complexes in the neuronal soma revealed by single quantum dot tracking.

Authors:  Anke Vermehren-Schmaedick; Wesley Krueger; Thomas Jacob; Damien Ramunno-Johnson; Agnieszka Balkowiec; Keith A Lidke; Tania Q Vu
Journal:  PLoS One       Date:  2014-04-14       Impact factor: 3.240
  7 in total

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