Literature DB >> 12189043

Antioxidant properties of a Tinospora cordifolia polysaccharide against iron-mediated lipid damage and gamma-ray induced protein damage.

Mahesh Subramanian1, Gajanan J Chintalwar, Subrata Chattopadhyay.   

Abstract

The antioxidant activity of an arabinogalactan polysaccharide (TSP) isolated from Tinospora cordifolia, an Indian medicinal plant, was studied. The polysaccharide showed good protection against iron-mediated lipid peroxidation of rat brain homogenate as revealed by the thiobarbituric acid reactive substances (TBARS) and lipid hydroperoxide (LOOH) assays. TSP also provided significant protection to protein against gamma-ray induced damage. The protective action can possibly be explained by its very high reactivity towards DPPH, superoxide radicals and the most damaging of radicals, the hydroxyl radical.

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Year:  2002        PMID： 12189043     DOI： 10.1179/135100002125000370

Source DB:  PubMed          Journal:  Redox Rep        ISSN： 1351-0002            Impact factor:   4.412


  15 in total

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Authors:  R A Bryan; O Zaragoza; T Zhang; G Ortiz; A Casadevall; E Dadachova
Journal:  Eukaryot Cell       Date:  2005-02

2.  Protective Role of Tinospora cordifolia against Lead-induced Hepatotoxicity.

Authors:  V Sharma; D Pandey
Journal:  Toxicol Int       Date:  2010-01

3.  Changes in MIDAS, Perceived Stress, Frontalis Muscle Activity and Non-Steroidal Anti-Inflammatory Drugs Usage in Patients with Migraine Headache without Aura following Ayurveda and Yoga Compared to Controls: An Open Labeled Non-Randomized Study.

Authors:  M S Vasudha; N K Manjunath; H R Nagendra
Journal:  Ann Neurosci       Date:  2018-09-11

4.  Tinospora cordifolia (Willd.) Hook. f. and Thoms. (Guduchi) - validation of the Ayurvedic pharmacology through experimental and clinical studies.

Authors:  Avnish K Upadhyay; Kaushal Kumar; Arvind Kumar; Hari S Mishra
Journal:  Int J Ayurveda Res       Date:  2010-04

5.  Evaluation of anti-depressant and anxiolytic activity of Rasayana Ghana Tablet (A compound Ayurvedic formulation) in albino mice.

Authors:  Yogesh S Deole; Sulakshan S Chavan; B K Ashok; B Ravishankar; A B Thakar; H M Chandola
Journal:  Ayu       Date:  2011-07

6.  In Vivo Delivery of Tinospora cordifolia Root Extract Preventing Radiation-Induced Dystrophies in Mice Ovaries.

Authors:  Riddhi Sharma
Journal:  Evid Based Complement Alternat Med       Date:  2015-08-18       Impact factor: 2.629

7.  Phytoremedial effect of Tinospora cordifolia against arsenic induced toxicity in Charles Foster rats.

Authors:  Vikas Kumar; Vivek Akhouri; Sushil Kumar Singh; Arun Kumar
Journal:  Biometals       Date:  2020-10-07       Impact factor: 2.949

8.  Tinospora cordifolia: One plant, many roles.

Authors:  Soham Saha; Shyamasree Ghosh
Journal:  Anc Sci Life       Date:  2012-04

9.  Rubia cordifolia, Fagonia cretica linn and Tinospora cordifolia exert neuroprotection by modulating the antioxidant system in rat hippocampal slices subjected to oxygen glucose deprivation.

Authors:  Avinash K Rawal; Manohar G Muddeshwar; Saibal K Biswas
Journal:  BMC Complement Altern Med       Date:  2004-08-13       Impact factor: 3.659

10.  Hypoglycemic and anti-hyperglycemic activity of Guduchi Satva in experimental animals.

Authors:  Rohit Sharma; Vijay Kumar; B K Ashok; R Galib; Pradeep Kumar Prajapati; B Ravishankar
Journal:  Ayu       Date:  2013-10
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