Literature DB >> 12187415

Ocular surface squamous neoplasia: report of an unusual case and review of the literature.

Karl W Whittaker1, Dipali Trivedi, J Bridger, S Sandramouli.   

Abstract

OBJECTIVE: To describe a case of leukoplakia and underlying intraepithelial squamous cell neoplasia of the palpebral conjunctiva presenting in a patient wearing an ocular prosthesis.
METHODS: The clinical presentation, histopathological findings and surgical outcome are described in a 62-year-old man in whom leukoplakic lesions of the palpebral conjunctiva in a socket fitted with an ocular prosthesis were noted in addition to squamous cell carcinoma of the lower lid skin.
RESULTS: Histopathological examination revealed islands of squamous cell carcinoma in the skin lesion and squamous cell carcinoma-in-situ in the leukoplakic conjunctival specimen. Successful tumour excision and lid reconstruction were performed.
CONCLUSION: This report highlights the successful treatment of long-standing conjunctival squamous cell carcinoma-in-situ associated with an ocular prosthesis and a general tendency to pre-neoplastic lesions of the skin. Regular examination of the sockets of patients wearing long-standing ocular prostheses is recommended.

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Mesh:

Year:  2002        PMID: 12187415     DOI: 10.1076/orbi.21.3.209.7173

Source DB:  PubMed          Journal:  Orbit        ISSN: 0167-6830


  6 in total

Review 1.  The aetiology and associations of conjunctival intraepithelial neoplasia.

Authors:  C A Kiire; B Dhillon
Journal:  Br J Ophthalmol       Date:  2006-01       Impact factor: 4.638

2.  Conjunctival squamous cell carcinoma due to ocular prostheses: a case report and review of literature.

Authors:  Rohit K Jain; Rutika Mehta; Sunil Badve
Journal:  Pathol Oncol Res       Date:  2010-04-08       Impact factor: 3.201

3.  Role of high resolution optical coherence tomography in diagnosing ocular surface squamous neoplasia with coexisting ocular surface diseases.

Authors:  Marwan Atallah; Madhura Joag; Anat Galor; Guillermo Amescua; Afshan Nanji; Jianhua Wang; Victor L Perez; Sander Dubovy; Carol L Karp
Journal:  Ocul Surf       Date:  2017-03-24       Impact factor: 6.268

4.  Conjunctival Squamous Cell Carcinoma due to Long-term Placement of Ocular Prosthesis.

Authors:  Ayato Hayashi; Masakazu Komoto; Takashi Matsumura; Masatoshi Horiguchi; Rica Tanaka; Atsushi Arakawa; Hiroshi Mizuno
Journal:  Plast Reconstr Surg Glob Open       Date:  2015-04-07

5.  A case of orbital sebaceous gland carcinoma developing in an anophthalmic socket 65 years after enucleation.

Authors:  Motoko Shibata; Yoshihiko Usui; Shunichiro Ueda; Hajime Matsumura; Toshitaka Nagao; Hiroshi Goto
Journal:  Clin Ophthalmol       Date:  2013-09-16

Review 6.  UV Protection in the Cornea: Failure and Rescue.

Authors:  Thomas Volatier; Björn Schumacher; Claus Cursiefen; Maria Notara
Journal:  Biology (Basel)       Date:  2022-02-10
  6 in total

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