Literature DB >> 12186275

Vaccines for Chlamydia trachomatis infections.

Luis M de la Maza1, Ellena M Peterson.   

Abstract

Members of the genus, Chlamydia, are obligate intracellular bacteria that have a unique developmental cycle. These organisms are widespread in nature and are common human pathogens. In this review, we describe new data related to the characterization of acquired immunity to Chlamydia trachomatis that is relevant to vaccine development. We also discuss recent work on vaccine candidates against this ubiquitous pathogen.

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Year:  2002        PMID: 12186275

Source DB:  PubMed          Journal:  Curr Opin Investig Drugs        ISSN: 1472-4472


  42 in total

1.  Vaccination with major outer membrane protein proteosomes elicits protection in mice against a Chlamydia respiratory challenge.

Authors:  Delia F Tifrea; Sukumar Pal; Deana N Toussi; Paola Massari; Luis M de la Maza
Journal:  Microbes Infect       Date:  2013-08-30       Impact factor: 2.700

2.  Intrauterine infection with plasmid-free Chlamydia muridarum reveals a critical role of the plasmid in chlamydial ascension and establishes a model for evaluating plasmid-independent pathogenicity.

Authors:  Jianlin Chen; Zhangsheng Yang; Xin Sun; Lingli Tang; Yiling Ding; Min Xue; Zhiguang Zhou; Joel Baseman; Guangming Zhong
Journal:  Infect Immun       Date:  2015-04-13       Impact factor: 3.441

3.  The Cryptic Plasmid Improves Chlamydia Fitness in Different Regions of the Gastrointestinal Tract.

Authors:  Jingyue Ma; Conghui He; Zhi Huo; Ying Xu; Bernard Arulanandam; Quanzhong Liu; Guangming Zhong
Journal:  Infect Immun       Date:  2020-02-20       Impact factor: 3.441

4.  Intravenous Inoculation with Chlamydia muridarum Leads to a Long-Lasting Infection Restricted to the Gastrointestinal Tract.

Authors:  Jin Dai; Tianyuan Zhang; Luying Wang; Lili Shao; Cuiming Zhu; Yuyang Zhang; Courtney Failor; Robert Schenken; Joel Baseman; Cheng He; Guangming Zhong
Journal:  Infect Immun       Date:  2016-07-21       Impact factor: 3.441

5.  Vaccination with the Chlamydia trachomatis major outer membrane protein can elicit an immune response as protective as that resulting from inoculation with live bacteria.

Authors:  Sukumar Pal; Ellena M Peterson; Luis M de la Maza
Journal:  Infect Immun       Date:  2005-12       Impact factor: 3.441

6.  Immunogenicity of a vaccine formulated with the Chlamydia trachomatis serovar F, native major outer membrane protein in a nonhuman primate model.

Authors:  Chunmei Cheng; Sukumar Pal; Ilham Bettahi; Kristie L Oxford; Peter A Barry; Luis M de la Maza
Journal:  Vaccine       Date:  2011-03-04       Impact factor: 3.641

7.  Induction of protection against vaginal shedding and infertility by a recombinant Chlamydia vaccine.

Authors:  Jennifer R Carmichael; Sukumar Pal; Delia Tifrea; Luis M de la Maza
Journal:  Vaccine       Date:  2011-05-24       Impact factor: 3.641

8.  Increased immunoaccessibility of MOMP epitopes in a vaccine formulated with amphipols may account for the very robust protection elicited against a vaginal challenge with Chlamydia muridarum.

Authors:  Delia F Tifrea; Sukumar Pal; Jean-Luc Popot; Melanie J Cocco; Luis M de la Maza
Journal:  J Immunol       Date:  2014-04-28       Impact factor: 5.422

9.  Serovar-specific immune responses to peptides of variable regions of Chlamydia trachomatis major outer membrane protein in serovar D-infected women.

Authors:  Pragya Srivastava; Rishein Gupta; Hem Chandra Jha; Rajneesh Jha; Apurb Rashmi Bhengraj; Sudha Salhan; Aruna Mittal
Journal:  Clin Exp Med       Date:  2008-09-25       Impact factor: 3.984

10.  Adaptive evolution of the Chlamydia trachomatis dominant antigen reveals distinct evolutionary scenarios for B- and T-cell epitopes: worldwide survey.

Authors:  Alexandra Nunes; Paulo J Nogueira; Maria J Borrego; João P Gomes
Journal:  PLoS One       Date:  2010-10-05       Impact factor: 3.240

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