Literature DB >> 12185154

Home based management in multiple sclerosis: results of a randomised controlled trial.

C Pozzilli1, M Brunetti, A M V Amicosante, C Gasperini, G Ristori, L Palmisano, M Battaglia.   

Abstract

BACKGROUND: Home based medical care is a popular alternative to standard hospital care but there is uncertainty about its cost-effectiveness.
OBJECTIVES: To compare the effectiveness and the costs of multidisciplinary home based care in multiple sclerosis with hospital care in a prospective randomised controlled trial with a one year follow up.
METHODS: 201 patients with clinically definite multiple sclerosis were studied. They were randomised in a ratio 2:1 to an intervention group (133) or a control group (68). They were assessed at baseline and one year after randomisation with validated measures of physical and psychological impairment and quality of life (SF-36 health survey). The costs to the National Health Service over the one year follow up were calculated by a cost minimisation analysis.
RESULTS: There were no differences in functional status between the home based care group and the hospital group. There was a significant difference between the two groups favouring home based management in four SF-36 health dimensions-general health, bodily pain, role-emotional, and social functioning (all p < or = 0.001). The cost of home based care was slightly less (822 euros/patient/year) than hospital care, mainly as a result of a reduction in hospital admissions.
CONCLUSIONS: Comprehensive planning of home based intervention implemented by an interdisciplinary team and designed specifically for people with multiple sclerosis may provide a cost-effective approach to management and improve the quality of life.

Entities:  

Mesh:

Year:  2002        PMID: 12185154      PMCID: PMC1738043          DOI: 10.1136/jnnp.73.3.250

Source DB:  PubMed          Journal:  J Neurol Neurosurg Psychiatry        ISSN: 0022-3050            Impact factor:   10.154


  34 in total

1.  Determinants of overall quality of life in secondary progressive MS: a longitudinal study.

Authors:  P O'Connor; L Lee; P T Ng; P Narayana; J S Wolinsky
Journal:  Neurology       Date:  2001-09-11       Impact factor: 9.910

2.  "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician.

Authors:  M F Folstein; S E Folstein; P R McHugh
Journal:  J Psychiatr Res       Date:  1975-11       Impact factor: 4.791

Review 3.  Multiple sclerosis.

Authors:  J H Noseworthy; C Lucchinetti; M Rodriguez; B G Weinshenker
Journal:  N Engl J Med       Date:  2000-09-28       Impact factor: 91.245

4.  Home or hospital for stroke rehabilitation? results of a randomized controlled trial : I: health outcomes at 6 months.

Authors:  C Anderson; S Rubenach; C N Mhurchu; M Clark; C Spencer; A Winsor
Journal:  Stroke       Date:  2000-05       Impact factor: 7.914

5.  Costs, quality of life and disease severity in multiple sclerosis: a cross-sectional study in Sweden.

Authors:  F Henriksson; S Fredrikson; T Masterman; B Jönsson
Journal:  Eur J Neurol       Date:  2001-01       Impact factor: 6.089

6.  Community services in multiple sclerosis: still a matter of chance.

Authors:  J A Freeman; A J Thompson
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-12       Impact factor: 10.154

7.  Physical rehabilitation has a positive effect on disability in multiple sclerosis patients.

Authors:  A Solari; G Filippini; P Gasco; L Colla; A Salmaggi; L La Mantia; M Farinotti; M Eoli; L Mendozzi
Journal:  Neurology       Date:  1999-01-01       Impact factor: 9.910

8.  Using the Short Form-36 with multiple sclerosis patients in five countries: a cross-cultural comparison.

Authors:  L Pfennings; L Cohen; D Miller; L Gerbaud; L Vleugels; J Freeman; D Vernay; S Biolay; P Ketelaer; A Thompson; C Polman; H van der Ploeg
Journal:  Psychol Rep       Date:  1999-08

9.  Clinical appropriateness: a key factor in outcome measure selection: the 36 item short form health survey in multiple sclerosis.

Authors:  J A Freeman; J C Hobart; D W Langdon; A J Thompson
Journal:  J Neurol Neurosurg Psychiatry       Date:  2000-02       Impact factor: 10.154

10.  Does adding MS-specific items to a generic measure (the SF-36) improve measurement?

Authors:  J A Freeman; J C Hobart; A J Thompson
Journal:  Neurology       Date:  2001-07-10       Impact factor: 9.910

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  15 in total

1.  A cross-sectional, multicentre study of the therapeutic management of multiple sclerosis relapses in Italy.

Authors:  Pietro Annovazzi; Valentina Tomassini; Benedetta Bodini; Laura Boffa; Massimiliano Calabrese; Eleonora Cocco; Cinzia Cordioli; Giovanna De Luca; Giovanni Frisullo; Antonio Gallo; Simona Malucchi; Damiano Paolicelli; Ilaria Pesci; Marta Radaelli; Paolo Ragonese; Luca Roccatagliata; Carla Tortorella; Marco Vercellino; Valentina Zipoli; Claudio Gasperini; Mariaemma Rodegher; Claudio Solaro
Journal:  Neurol Sci       Date:  2012-03-11       Impact factor: 3.307

2.  Telemedicine for Monitoring MS Activity and Progression.

Authors:  Nuria Sola-Valls; Yolanda Blanco; Maria Sepúlveda; Eugenia Martinez-Hernandez; Albert Saiz
Journal:  Curr Treat Options Neurol       Date:  2015-11       Impact factor: 3.598

3.  Home or away? Choosing a setting for a falls-prevention program for people with multiple sclerosis.

Authors:  Hilary Gunn; Davide Cattaneo; Marcia Finlayson; Jennifer Freeman; Jacob J Sosnoff
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Review 4.  [Quality of life in multiple sclerosis. Measures, relevance, problems, and perspectives].

Authors:  W Pöllmann; C Busch; R Voltz
Journal:  Nervenarzt       Date:  2005-02       Impact factor: 1.214

5.  Positive effects of tertiary centres for amyotrophic lateral sclerosis on outcome and use of hospital facilities.

Authors:  A Chiò; E Bottacchi; C Buffa; R Mutani; G Mora
Journal:  J Neurol Neurosurg Psychiatry       Date:  2006-04-13       Impact factor: 10.154

Review 6.  Avoiding hospital admission through provision of hospital care at home: a systematic review and meta-analysis of individual patient data.

Authors:  Sasha Shepperd; Helen Doll; Robert M Angus; Mike J Clarke; Steve Iliffe; Lalit Kalra; Nicoletta Aimonio Ricauda; Vittoria Tibaldi; Andrew D Wilson
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Review 7.  Psychosocial interventions in people with multiple sclerosis: a review.

Authors:  K S Malcomson; L Dunwoody; A S Lowe-Strong
Journal:  J Neurol       Date:  2007-02-14       Impact factor: 4.849

8.  Multiple Sclerosis at Home Access (MAHA): An Initiative to Improve Care in the Community.

Authors:  Kathleen Healey; Rana Zabad; Lufei Young; Aubrie Lindner; Nancy Lenz; Renee Stewart; Mary Charlton
Journal:  Int J MS Care       Date:  2019 May-Jun

Review 9.  Multidisciplinary rehabilitation for adults with multiple sclerosis.

Authors:  F Khan; L Turner-Stokes; L Ng; T Kilpatrick
Journal:  Cochrane Database Syst Rev       Date:  2007-04-18

Review 10.  Identifying and Managing Suicidality in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome.

Authors:  Lily Chu; Meghan Elliott; Eleanor Stein; Leonard A Jason
Journal:  Healthcare (Basel)       Date:  2021-05-25
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