| Literature DB >> 12183183 |
Abstract
The activity state of a gene is determined not only by sequence-specific regulatory factors but also by a complex network of co-acting proteins. Many of these proteins directly or indirectly affect the structure of the chromatin environment into which the gene is embedded. Recent studies of histone and DNA modifications support and refine the concept of the chromatin environment being key to the establishment and maintenance of transcriptional activity or repression.Mesh:
Substances:
Year: 2002 PMID: 12183183 DOI: 10.1016/s1369-5266(02)00287-x
Source DB: PubMed Journal: Curr Opin Plant Biol ISSN: 1369-5266 Impact factor: 7.834