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Literature DB >> 12183107

Positron emission tomography: the conceptual idea using a multidisciplinary approach.

Anne M J Paans¹, Aren van Waarde, Philip H Elsinga, Antoon T M Willemsen, Willem Vaalburg.

Abstract

Positron emission tomography (PET) is a method for quantitatively measuring biochemical and physiological processes in vivo by using radiopharmaceuticals labeled with positron-emitting radionuclides such as 11C, 13N, 15O, and 18F and by measuring the annihilation radiation using a coincidence technique. This technique is also used for measurement of the pharmacokinetics of labeled drugs and measurement of the effects of drugs on metabolism. Deviations from normal metabolism can be measured and insight into biological processes responsible for diseases can be obtained.

Entities: Chemical

Mesh：

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Year: 2002 PMID： 12183107 DOI： 10.1016/s1046-2023(02)00075-0

Source DB: PubMed Journal: Methods ISSN： 1046-2023 Impact factor: 3.608

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Cited

8 in total

Review 1. Neuroimaging Methods for Nursing Science.

Authors: Sebastian W Atalla; Laura Beth Kalvas; Jenna L Campbell; Alison R Anderson; Ronald L Cowan; Kathy Wright; Angela C Humbel; Todd B Monroe
Journal: Nurs Res Date: 2020 May/Jun Impact factor: 2.381

2. Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6.

Authors: Paris R Watson; Ping Bai; Changning Wang; Abigail D Cragin; Jacob M Hooker; David W Christianson
Journal: Biochemistry Date: 2022-09-08 Impact factor: 3.321

3. Organomediated cleavage of benzoyl group enables an efficient synthesis of 1-(6-nitropyridin-2-yl)thiourea and its application for developing ¹⁸F-labeled PET tracers.

Authors: Junfeng Wang; Kazue Takahashi; Timothy M Shoup; Lichong Gong; Yingbo Li; Georges El Fakhri; Zhaoda Zhang; Anna-Liisa Brownell
Journal: Bioorg Chem Date: 2022-04-12 Impact factor: 5.307

8. Nitrone-Modified Gold Nanoparticles: Synthesis, Characterization, and Their Potential as ¹⁸F-Labeled Positron Emission Tomography Probes via I-SPANC.

Authors: Sara Ghiassian; Lihai Yu; Pierangelo Gobbo; Ali Nazemi; Tommaso Romagnoli; Wilson Luo; Leonard G Luyt; Mark S Workentin
Journal: ACS Omega Date: 2019-11-08

8 in total

Positron emission tomography: the conceptual idea using a multidisciplinary approach.

Review 1. Neuroimaging Methods for Nursing Science.

2. Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6.

3. Organomediated cleavage of benzoyl group enables an efficient synthesis of 1-(6-nitropyridin-2-yl)thiourea and its application for developing ¹⁸F-labeled PET tracers.

4. Use of Molecular Imaging in Clinical Drug Development: a Systematic Review.

Review 5. PET-MR and SPECT-MR multimodality probes: Development and challenges.

Review 6. Iodine-124: a promising positron emitter for organic PET chemistry.

Review 7. Methods to Enhance the Metabolic Stability of Peptide-Based PET Radiopharmaceuticals.

8. Nitrone-Modified Gold Nanoparticles: Synthesis, Characterization, and Their Potential as ¹⁸F-Labeled Positron Emission Tomography Probes via I-SPANC.

Positron emission tomography: the conceptual idea using a multidisciplinary approach.

Review 1. Neuroimaging Methods for Nursing Science.

2. Aromatic Ring Fluorination Patterns Modulate Inhibitory Potency of Fluorophenylhydroxamates Complexed with Histone Deacetylase 6.

3. Organomediated cleavage of benzoyl group enables an efficient synthesis of 1-(6-nitropyridin-2-yl)thiourea and its application for developing 18F-labeled PET tracers.

4. Use of Molecular Imaging in Clinical Drug Development: a Systematic Review.

Review 5. PET-MR and SPECT-MR multimodality probes: Development and challenges.

Review 6. Iodine-124: a promising positron emitter for organic PET chemistry.

Review 7. Methods to Enhance the Metabolic Stability of Peptide-Based PET Radiopharmaceuticals.

8. Nitrone-Modified Gold Nanoparticles: Synthesis, Characterization, and Their Potential as 18F-Labeled Positron Emission Tomography Probes via I-SPANC.

3. Organomediated cleavage of benzoyl group enables an efficient synthesis of 1-(6-nitropyridin-2-yl)thiourea and its application for developing ¹⁸F-labeled PET tracers.

8. Nitrone-Modified Gold Nanoparticles: Synthesis, Characterization, and Their Potential as ¹⁸F-Labeled Positron Emission Tomography Probes via I-SPANC.