OBJECTIVE: To investigate the genetic and environmental influences on body-fat measures including waist circumference (WC), waist-to-hip ratio (WHR), and body mass index (BMI) among African-American men and women. RESEARCH METHODS AND PROCEDURES: Measurements were taken as part of the Carolina African American Twin Study of Aging. This sample currently comprises 146 same-sex African-American twins with an average age of 50 years (range, 22 to 88 years). This analysis included 26 monozygotic and 29 dizygotic men and 45 monozygotic and 46 dizygotic women. Maximum likelihood quantitative genetic analysis was used. RESULTS: In men, additive genetic effects accounted for 77% of the variance in WC, 59% in WHR, and 89% in BMI. In women, additive genetic effects accounted for 76% of the variance in WC, 56% in WHR, and 73% in BMI. The remaining variance in both men and women was attributed to unique environmental effects (WC, 21%; WHR, 36%; BMI, 11% in men and WC, 22%; WHR, 38%; BMI, 27% in women) and age (WC, 2%; WHR, 5% in men and WC, 2%; WHR, 6% in women). When BMI was controlled in the analysis of WC and WHR, it accounted for a portion of the genetic and environmental variance in WHR and over one-half of the genetic and environmental variance in WC. DISCUSSION: There are both genetic and environmental influences on WC, WHR, and BMI, and independent of BMI, there are genetic and environmental effects on WC and WHR among both genders. The results from this African-American twin sample are similar to findings among white twin samples.
OBJECTIVE: To investigate the genetic and environmental influences on body-fat measures including waist circumference (WC), waist-to-hip ratio (WHR), and body mass index (BMI) among African-American men and women. RESEARCH METHODS AND PROCEDURES: Measurements were taken as part of the Carolina African American Twin Study of Aging. This sample currently comprises 146 same-sex African-American twins with an average age of 50 years (range, 22 to 88 years). This analysis included 26 monozygotic and 29 dizygotic men and 45 monozygotic and 46 dizygotic women. Maximum likelihood quantitative genetic analysis was used. RESULTS: In men, additive genetic effects accounted for 77% of the variance in WC, 59% in WHR, and 89% in BMI. In women, additive genetic effects accounted for 76% of the variance in WC, 56% in WHR, and 73% in BMI. The remaining variance in both men and women was attributed to unique environmental effects (WC, 21%; WHR, 36%; BMI, 11% in men and WC, 22%; WHR, 38%; BMI, 27% in women) and age (WC, 2%; WHR, 5% in men and WC, 2%; WHR, 6% in women). When BMI was controlled in the analysis of WC and WHR, it accounted for a portion of the genetic and environmental variance in WHR and over one-half of the genetic and environmental variance in WC. DISCUSSION: There are both genetic and environmental influences on WC, WHR, and BMI, and independent of BMI, there are genetic and environmental effects on WC and WHR among both genders. The results from this African-American twin sample are similar to findings among white twin samples.
Authors: J M Hester; M R Wing; J Li; N D Palmer; J Xu; P J Hicks; B H Roh; J M Norris; L E Wagenknecht; C D Langefeld; B I Freedman; D W Bowden; M C Y Ng Journal: Int J Obes (Lond) Date: 2011-07-12 Impact factor: 5.095
Authors: Maggie C Y Ng; Jessica M Hester; Maria R Wing; Jiang Li; Jianzhao Xu; Pamela J Hicks; Bong H Roh; Lingyi Lu; Jasmin Divers; Carl D Langefeld; Barry I Freedman; Nichole D Palmer; Donald W Bowden Journal: Obesity (Silver Spring) Date: 2011-06-23 Impact factor: 5.002
Authors: Władysław Mynarski; Jarosław Cholewa; Michał Rozpara; Zbigniew Borek; Krzysztof Strojek; Agnieszka Nawrocka Journal: J Phys Ther Sci Date: 2015-08-21
Authors: Karri Silventoinen; Weilong Li; Aline Jelenkovic; Reijo Sund; Yoshie Yokoyama; Sari Aaltonen; Maarit Piirtola; Masumi Sugawara; Mami Tanaka; Satoko Matsumoto; Laura A Baker; Catherine Tuvblad; Per Tynelius; Finn Rasmussen; Jeffrey M Craig; Richard Saffery; Gonneke Willemsen; Meike Bartels; Catharina E M van Beijsterveldt; Nicholas G Martin; Sarah E Medland; Grant W Montgomery; Paul Lichtenstein; Robert F Krueger; Matt McGue; Shandell Pahlen; Kaare Christensen; Axel Skytthe; Kirsten O Kyvik; Kimberly J Saudino; Lise Dubois; Michel Boivin; Mara Brendgen; Ginette Dionne; Frank Vitaro; Vilhelmina Ullemar; Catarina Almqvist; Patrik K E Magnusson; Robin P Corley; Brooke M Huibregtse; Ariel Knafo-Noam; David Mankuta; Lior Abramson; Claire M A Haworth; Robert Plomin; Morten Bjerregaard-Andersen; Henning Beck-Nielsen; Morten Sodemann; Glen E Duncan; Dedra Buchwald; S Alexandra Burt; Kelly L Klump; Clare H Llewellyn; Abigail Fisher; Dorret I Boomsma; Thorkild I A Sørensen; Jaakko Kaprio Journal: Int J Obes (Lond) Date: 2022-08-09 Impact factor: 5.551
Authors: Ching-Ti Liu; Keri L Monda; Kira C Taylor; Leslie Lange; Ellen W Demerath; Walter Palmas; Mary K Wojczynski; Jaclyn C Ellis; Mara Z Vitolins; Simin Liu; George J Papanicolaou; Marguerite R Irvin; Luting Xue; Paula J Griffin; Michael A Nalls; Adebowale Adeyemo; Jiankang Liu; Guo Li; Edward A Ruiz-Narvaez; Wei-Min Chen; Fang Chen; Brian E Henderson; Robert C Millikan; Christine B Ambrosone; Sara S Strom; Xiuqing Guo; Jeanette S Andrews; Yan V Sun; Thomas H Mosley; Lisa R Yanek; Daniel Shriner; Talin Haritunians; Jerome I Rotter; Elizabeth K Speliotes; Megan Smith; Lynn Rosenberg; Josyf Mychaleckyj; Uma Nayak; Ida Spruill; W Timothy Garvey; Curtis Pettaway; Sarah Nyante; Elisa V Bandera; Angela F Britton; Alan B Zonderman; Laura J Rasmussen-Torvik; Yii-Der Ida Chen; Jingzhong Ding; Kurt Lohman; Stephen B Kritchevsky; Wei Zhao; Patricia A Peyser; Sharon L R Kardia; Edmond Kabagambe; Ulrich Broeckel; Guanjie Chen; Jie Zhou; Sylvia Wassertheil-Smoller; Marian L Neuhouser; Evadnie Rampersaud; Bruce Psaty; Charles Kooperberg; Joann E Manson; Lewis H Kuller; Heather M Ochs-Balcom; Karen C Johnson; Lara Sucheston; Jose M Ordovas; Julie R Palmer; Christopher A Haiman; Barbara McKnight; Barbara V Howard; Diane M Becker; Lawrence F Bielak; Yongmei Liu; Matthew A Allison; Struan F A Grant; Gregory L Burke; Sanjay R Patel; Pamela J Schreiner; Ingrid B Borecki; Michele K Evans; Herman Taylor; Michele M Sale; Virginia Howard; Christopher S Carlson; Charles N Rotimi; Mary Cushman; Tamara B Harris; Alexander P Reiner; L Adrienne Cupples; Kari E North; Caroline S Fox Journal: PLoS Genet Date: 2013-08-15 Impact factor: 5.917