Literature DB >> 12176778

Nasopharyngeal carcinoma.

A T C Chan1, P M L Teo, P J Johnson.   

Abstract

Nasopharyngeal carcinoma (NPC) is endemic in southern China where genetic abnormalities and Epstein-Barr virus (EBV) infection are critical in the pathogenesis of the disease. Circulating EBV-DNA has been shown to improve prognostication and monitoring of NPC patients. Radiotherapy is the mainstay treatment for early disease and concurrent cisplatin/radiotherapy has been demonstrated to prolong survival in locoregionally advanced disease. Ongoing studies of targeting agents and immunotherapeutic approaches may further improve treatment results.

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Year:  2002        PMID： 12176778     DOI： 10.1093/annonc/mdf179

Source DB:  PubMed          Journal:  Ann Oncol        ISSN： 0923-7534            Impact factor:   32.976


  93 in total

1.  K252a induces anoikis-sensitization with suppression of cellular migration in Epstein-Barr virus (EBV)--associated nasopharyngeal carcinoma cells.

Authors:  Yuen-Keng Ng; Elaine Yue Ling Wong; Cecilia Pik Yuk Lau; Jessica Pui Lan Chan; Sze Chuen Cesar Wong; Andrew Sai-Kit Chan; Maggie Pui Chun Kwan; Sai-Wah Tsao; Chi-Man Tsang; Paul Bo San Lai; Anthony Tak Cheung Chan; Vivian Wai Yan Lui
Journal:  Invest New Drugs       Date:  2010-08-07       Impact factor: 3.850

2.  Distinct memory CD4+ T-cell subsets mediate immune recognition of Epstein Barr virus nuclear antigen 1 in healthy virus carriers.

Authors:  Kevin N Heller; Jenica Upshaw; Beza Seyoum; Henry Zebroski; Christian Münz
Journal:  Blood       Date:  2006-09-19       Impact factor: 22.113

3.  Unusual cancer in primary Sjögren syndrome.

Authors:  Wen-Sen Lai; Feng-Cheng Liu; Chih-Hung Wang; Hsin-Chien Chen
Journal:  Can Fam Physician       Date:  2014-10       Impact factor: 3.275

4.  Preferential cytotoxicity of the type I ribosome inactivating protein alpha-momorcharin on human nasopharyngeal carcinoma cells under normoxia and hypoxia.

Authors:  Wen Liang Pan; Jack Ho Wong; Evandro Fei Fang; Yau Sang Chan; Tzi Bun Ng; Randy Chi Fai Cheung
Journal:  Biochem Pharmacol       Date:  2014-03-14       Impact factor: 5.858

5.  Hypoxia-targeting by tirapazamine (TPZ) induces preferential growth inhibition of nasopharyngeal carcinoma cells with Chk1/2 activation.

Authors:  Bo Hong; Vivian W Y Lui; Edwin P Hui; Margaret H L Ng; Suk-Hang Cheng; Fion L Sung; Chi-Man Tsang; Sai-Wah Tsao; Anthony Tak-Cheung Chan
Journal:  Invest New Drugs       Date:  2009-12-16       Impact factor: 3.850

6.  Niflumic acid exhibits anti-tumor activity in nasopharyngeal carcinoma cells through affecting the expression of ERK1/2 and the activity of MMP2 and MMP9.

Authors:  Shengqun Luo; Guoliang Huang; Ziyou Wang; Zheng Wan; Hua Chen; Dan Liao; Chuyan Chen; Huahui Li; Binbin Li; Liyong Chen; Zunnan Huang; Zhiwei He
Journal:  Int J Clin Exp Pathol       Date:  2015-09-01

7.  Epstein-Barr virus encoded latent membrane protein 1 regulates mTOR signaling pathway genes which predict poor prognosis of nasopharyngeal carcinoma.

Authors:  Jing Chen; Chun-Fang Hu; Jing-Hui Hou; Qiong Shao; Li-Xu Yan; Xiao-Feng Zhu; Yi-Xin Zeng; Jian-Yong Shao
Journal:  J Transl Med       Date:  2010-03-26       Impact factor: 5.531

8.  Transcriptional regulation of BRD7 expression by Sp1 and c-Myc.

Authors:  Huaying Liu; Ming Zhou; Xiaomin Luo; Liming Zhang; Zhaoxia Niu; Cong Peng; Jian Ma; Shuping Peng; Houde Zhou; Bo Xiang; Xiayu Li; Shufang Li; Jiajin He; Xiaoling Li; Guiyuan Li
Journal:  BMC Mol Biol       Date:  2008-12-27       Impact factor: 2.946

9.  Emerging concepts in biomarker discovery; the US-Japan Workshop on Immunological Molecular Markers in Oncology.

Authors:  Hideaki Tahara; Marimo Sato; Magdalena Thurin; Ena Wang; Lisa H Butterfield; Mary L Disis; Bernard A Fox; Peter P Lee; Samir N Khleif; Jon M Wigginton; Stefan Ambs; Yasunori Akutsu; Damien Chaussabel; Yuichiro Doki; Oleg Eremin; Wolf Hervé Fridman; Yoshihiko Hirohashi; Kohzoh Imai; James Jacobson; Masahisa Jinushi; Akira Kanamoto; Mohammed Kashani-Sabet; Kazunori Kato; Yutaka Kawakami; John M Kirkwood; Thomas O Kleen; Paul V Lehmann; Lance Liotta; Michael T Lotze; Michele Maio; Anatoli Malyguine; Giuseppe Masucci; Hisahiro Matsubara; Shawmarie Mayrand-Chung; Kiminori Nakamura; Hiroyoshi Nishikawa; A Karolina Palucka; Emanuel F Petricoin; Zoltan Pos; Antoni Ribas; Licia Rivoltini; Noriyuki Sato; Hiroshi Shiku; Craig L Slingluff; Howard Streicher; David F Stroncek; Hiroya Takeuchi; Minoru Toyota; Hisashi Wada; Xifeng Wu; Julia Wulfkuhle; Tomonori Yaguchi; Benjamin Zeskind; Yingdong Zhao; Mai-Britt Zocca; Francesco M Marincola
Journal:  J Transl Med       Date:  2009-06-17       Impact factor: 5.531

10.  Commentary: mechanistic considerations for associations between formaldehyde exposure and nasopharyngeal carcinoma.

Authors:  Chad M Thompson; Roland C Grafström
Journal:  Environ Health       Date:  2009-11-25       Impact factor: 5.984
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