Literature DB >> 12176410

Sirolimus inhibits growth of human hepatoma cells in contrast to tacrolimus which promotes cell growth.

G Schumacher1, M Oidtmann, S Rosewicz, J Langrehr, S Jonas, A R Mueller, A Rueggeberg, R Neuhaus, M Bahra, D Jacob, H Gerlach, P Neuhaus.   

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Year:  2002        PMID： 12176410     DOI： 10.1016/s0041-1345(02)02899-3

Source DB:  PubMed          Journal:  Transplant Proc        ISSN： 0041-1345            Impact factor:   1.066


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  12 in total

Review 1.  Hepatocellular carcinoma and liver transplantation: clinical perspective on molecular targeted strategies.

Authors:  Yasunobu Matsuda; Takafumi Ichida; Manabu Fukumoto
Journal:  Med Mol Morphol       Date:  2011-09-16       Impact factor: 2.309

2.  Sirolimus inhibits growth of human hepatoma cells alone or combined with tacrolimus, while tacrolimus promotes cell growth.

Authors:  Guido Schumacher; Marijke Oidtmann; Anne Rueggeberg; Dietmar Jacob; Sven Jonas; Jan-M Langrehr; Ruth Neuhaus; Marcus Bahra; Peter Neuhaus
Journal:  World J Gastroenterol       Date:  2005-03-14       Impact factor: 5.742

Review 3.  Mammalian target of rapamycin inhibition in hepatocellular carcinoma.

Authors:  René E Ashworth; Jennifer Wu
Journal:  World J Hepatol       Date:  2014-11-27

4.  A prospective randomised, open-labeled, trial comparing sirolimus-containing versus mTOR-inhibitor-free immunosuppression in patients undergoing liver transplantation for hepatocellular carcinoma.

Authors:  Andreas A Schnitzbauer; Carl Zuelke; Christian Graeb; Justine Rochon; Itxarone Bilbao; Patrizia Burra; Koert P de Jong; Christophe Duvoux; Norman M Kneteman; Rene Adam; Wolf O Bechstein; Thomas Becker; Susanne Beckebaum; Olivier Chazouillères; Umberto Cillo; Michele Colledan; Fred Fändrich; Jean Gugenheim; Johann P Hauss; Michael Heise; Ernest Hidalgo; Neville Jamieson; Alfred Königsrainer; Philipp E Lamby; Jan P Lerut; Heikki Mäkisalo; Raimund Margreiter; Vincenzo Mazzaferro; Ingrid Mutzbauer; Gerd Otto; Georges-Philippe Pageaux; Antonio D Pinna; Jacques Pirenne; Magnus Rizell; Giorgio Rossi; Lionel Rostaing; Andre Roy; Victor Sanchez Turrion; Jan Schmidt; Roberto I Troisi; Bart van Hoek; Umberto Valente; Philippe Wolf; Heiner Wolters; Darius F Mirza; Tim Scholz; Rudolf Steininger; Gunnar Soderdahl; Simone I Strasser; Karl-Walter Jauch; Peter Neuhaus; Hans J Schlitt; Edward K Geissler
Journal:  BMC Cancer       Date:  2010-05-11       Impact factor: 4.430

5.  Liver Transplantation for HCC: A Review.

Authors:  Rahul Kakodkar; A S Soin
Journal:  Indian J Surg       Date:  2011-12-27       Impact factor: 0.656

Review 6.  Malignancy in kidney transplant recipients.

Authors:  Anil Kapoor
Journal:  Drugs       Date:  2008       Impact factor: 9.546

7.  Effects of the mTOR inhibitor sirolimus in patients with hepatocellular and cholangiocellular cancer.

Authors:  Magnus Rizell; Mats Andersson; Christian Cahlin; Larsolof Hafström; Michael Olausson; Per Lindnér
Journal:  Int J Clin Oncol       Date:  2008-02-29       Impact factor: 3.402

8.  Impact of rapamycin on liver regeneration.

Authors:  Daniel Palmes; Andree Zibert; Tymotheus Budny; Ralf Bahde; Evgeny Minin; Linus Kebschull; Jens Hölzen; Hartmut Schmidt; Hans-Ullrich Spiegel
Journal:  Virchows Arch       Date:  2008-05       Impact factor: 4.064

Review 9.  Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.

Authors:  William H Chappell; Linda S Steelman; Jacquelyn M Long; Ruth C Kempf; Stephen L Abrams; Richard A Franklin; Jörg Bäsecke; Franca Stivala; Marco Donia; Paolo Fagone; Graziella Malaponte; Maria C Mazzarino; Ferdinando Nicoletti; Massimo Libra; Danijela Maksimovic-Ivanic; Sanja Mijatovic; Giuseppe Montalto; Melchiorre Cervello; Piotr Laidler; Michele Milella; Agostino Tafuri; Antonio Bonati; Camilla Evangelisti; Lucio Cocco; Alberto M Martelli; James A McCubrey
Journal:  Oncotarget       Date:  2011-03

Review 10.  Targeted therapy for hepatocellular carcinoma: novel agents on the horizon.

Authors:  Melchiorre Cervello; James A McCubrey; Antonella Cusimano; Nadia Lampiasi; Antonina Azzolina; Giuseppe Montalto
Journal:  Oncotarget       Date:  2012-03
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