Literature DB >> 12176399

Influence of the APOC3 -2854T>G polymorphism on plasma lipid levels: effect of age and gender.

Anne Marie Minihane1, Yvonne E Finnegan, Philippa Talmud, Elizabeth C Leigh-Firbank, Christine M Williams.   

Abstract

The APOC3 -2854T>G polymorphism lies in the APOC3-A4 intergenic region. In a group of healthy adults, this polymorphism was associated with circulating triglycerides, with 55% lower fasting levels in the homozygous wild-type (TT) compared to the homozygous rare allele (GG) genotype. Age and gender had a significant impact on genotype-triglyceride interactions.

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Year:  2002        PMID： 12176399     DOI： 10.1016/s1388-1981(02)00264-0

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN： 0006-3002


  4 in total

1.  The apolipoprotein CIII T2854G variants are associated with postprandial triacylglycerol concentrations in normolipidemic Korean men.

Authors:  Sang-Koo Woo; Hyun-Sik Kang
Journal:  J Hum Genet       Date:  2003-09-27       Impact factor: 3.172

2.  Effects of variations in the APOA1/C3/A4/A5 gene cluster on different parameters of postprandial lipid metabolism in healthy young men.

Authors:  Javier Delgado-Lista; Francisco Perez-Jimenez; Juan Ruano; Pablo Perez-Martinez; Francisco Fuentes; Juan Criado-Garcia; Laurence D Parnell; Antonio Garcia-Rios; Jose M Ordovas; Jose Lopez-Miranda
Journal:  J Lipid Res       Date:  2010-01       Impact factor: 5.922

3.  Interactions of the apolipoprotein C-III 3238C>G polymorphism and alcohol consumption on serum triglyceride levels.

Authors:  Yin Ruixing; Li Yiyang; Li Meng; Li Kela; Long Xingjiang; Zhang Lin; Liu Wanying; Wu Jinzhen; Yang Dezhai; Lin Weixiong
Journal:  Lipids Health Dis       Date:  2010-08-17       Impact factor: 3.876

4.  Lipoprotein genotype and conserved pathway for exceptional longevity in humans.

Authors:  Gil Atzmon; Marielisa Rincon; Clyde B Schechter; Alan R Shuldiner; Richard B Lipton; Aviv Bergman; Nir Barzilai
Journal:  PLoS Biol       Date:  2006-04-04       Impact factor: 8.029
  4 in total

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