Literature DB >> 12176351

Gem GTPase: between a ROCK and a hard place.

Michael F Olson1.   

Abstract

Gem GTPase is a member of a protein family that includes Rad, Rem and Rem2. Although until recently precious little was known about the function of Gem, recent studies have revealed that Gem may influence cell morphology by antagonising the actions of the Rho GTPase effector protein ROCK I.

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Year:  2002        PMID: 12176351     DOI: 10.1016/s0960-9822(02)00968-5

Source DB:  PubMed          Journal:  Curr Biol        ISSN: 0960-9822            Impact factor:   10.834


  3 in total

1.  Rem2 GTPase maintains survival of human embryonic stem cells as well as enhancing reprogramming by regulating p53 and cyclin D1.

Authors:  Michael J Edel; Cristina Menchon; Sergio Menendez; Antonella Consiglio; Angel Raya; Juan Carlos Izpisua Belmonte
Journal:  Genes Dev       Date:  2010-03-15       Impact factor: 11.361

2.  Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.

Authors:  Yuichiro Nakata; Takeshi Ueda; Akiko Nagamachi; Norimasa Yamasaki; Ken-Ichiro Ikeda; Yasuyuki Sera; Keiyo Takubo; Akinori Kanai; Hideaki Oda; Masashi Sanada; Seishi Ogawa; Kohichiro Tsuji; Yasuhiro Ebihara; Linda Wolff; Zen-Ichiro Honda; Toshio Suda; Toshiya Inaba; Hiroaki Honda
Journal:  Blood       Date:  2017-02-16       Impact factor: 22.113

3.  Expression, purification, crystallization and preliminary crystallographic analysis of human Rad GTPase.

Authors:  Arry Yanuar; Shigeru Sakurai; Ken Kitano; Toshio Hakoshima
Journal:  Acta Crystallogr Sect F Struct Biol Cryst Commun       Date:  2005-10-20
  3 in total

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