Literature DB >> 12176315

A new trigger for T cells.

Mark M Davis1.   

Abstract

Understanding the early events in T cell activation and signaling is an active area of research. A recent study has described a new trigger for T cell activation, involving a TCR-ligand-induced conformational change in CD3epsilon that permits binding of the adaptor protein Nck.

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Year:  2002        PMID： 12176315     DOI： 10.1016/s0092-8674(02)00865-6

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  16 in total

1.  Crystal structure of the human T cell receptor CD3 epsilon gamma heterodimer complexed to the therapeutic mAb OKT3.

Authors:  Lars Kjer-Nielsen; Michelle A Dunstone; Lyudmila Kostenko; Lauren K Ely; Travis Beddoe; Nicole A Mifsud; Anthony W Purcell; Andrew G Brooks; James McCluskey; Jamie Rossjohn
Journal:  Proc Natl Acad Sci U S A       Date:  2004-05-10       Impact factor: 11.205

Review 2.  A role for "self" in T-cell activation.

Authors:  Michelle Krogsgaard; Jeremy Juang; Mark M Davis
Journal:  Semin Immunol       Date:  2007-06-04       Impact factor: 11.130

3.  The SCHOOL of nature: I. Transmembrane signaling.

Authors:  Alexander B Sigalov
Journal:  Self Nonself       Date:  2010-01

4.  Boosting functional avidity of CD8+ T cells by vaccinia virus vaccination depends on intrinsic T-cell MyD88 expression but not the inflammatory milieu.

Authors:  Zhidong Hu; Jing Wang; Yanmin Wan; Lingyan Zhu; Xiaonan Ren; Sugan Qiu; Yanqin Ren; Songhua Yuan; Xiangqing Ding; Jian Chen; Chenli Qiu; Jun Sun; Xiaoyan Zhang; Jim Xiang; Chao Qiu; Jianqing Xu
Journal:  J Virol       Date:  2014-02-19       Impact factor: 5.103

5.  Original Research: Analysis of hepatic microRNA alterations in response to hepatitis B virus infection and pegylated interferon alpha-2a treatment.

Authors:  Thananya Jinato; Natthaya Chuaypen; Witthaya Poomipak; Kesmanee Praianantathavorn; Jarika Makkoch; Rattanaporn Kiatbumrung; Kanisa Jampoka; Pisit Tangkijvanich; Sunchai Payungporn
Journal:  Exp Biol Med (Maywood)       Date:  2016-05-04

6.  Transcriptome profiling and digital gene expression analysis of Nile tilapia (Oreochromis niloticus) infected by Streptococcus agalactiae.

Authors:  Rui Zhang; Li-li Zhang; Xing Ye; Yuan-yuan Tian; Cheng-fei Sun; Mai-xin Lu; Jun-jie Bai
Journal:  Mol Biol Rep       Date:  2013-09-26       Impact factor: 2.316

Review 7.  Mechanisms for T cell receptor triggering.

Authors:  P Anton van der Merwe; Omer Dushek
Journal:  Nat Rev Immunol       Date:  2010-12-03       Impact factor: 53.106

8.  T cell receptor engagement by peptide-MHC ligands induces a conformational change in the CD3 complex of thymocytes.

Authors:  Diana Gil; Adam G Schrum; Balbino Alarcón; Ed Palmer
Journal:  J Exp Med       Date:  2005-02-21       Impact factor: 14.307

9.  Twisting tails exposed: the evidence for TCR conformational change.

Authors:  Susan E Levin; Arthur Weiss
Journal:  J Exp Med       Date:  2005-02-21       Impact factor: 14.307

Review 10.  Co-Receptor CD8-Mediated Modulation of T-Cell Receptor Functional Sensitivity and Epitope Recognition Degeneracy.

Authors:  Barbara Szomolay; Tamsin Williams; Linda Wooldridge; Hugo Antonius van den Berg
Journal:  Front Immunol       Date:  2013-10-21       Impact factor: 7.561
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